Oxidative stress regulation and related metabolic pathways in epithelial–mesenchymal transition of breast cancer stem cells
Epithelial–mesenchymal transition (EMT) is a cell remodeling process in which epithelial
cells undergo a reversible phenotype switch via the loss of adhesion capacity and …
cells undergo a reversible phenotype switch via the loss of adhesion capacity and …
Effect of modulation of epithelial‑mesenchymal transition regulators Snail1 and Snail2 on cancer cell radiosensitivity by targeting of the cell cycle, cell apoptosis and …
G Assani, Y Zhou - Oncology letters, 2019 - spandidos-publications.com
Cancer is one of the leading causes of cancer‑associated mortality worldwide. Several
strategies of treatment, including radiotherapy, have been developed and used to treat this …
strategies of treatment, including radiotherapy, have been developed and used to treat this …
[HTML][HTML] LncRNA MALAT1 exerts oncogenic functions in lung adenocarcinoma by targeting miR-204
J Li, J Wang, Y Chen, S Li, M Jin, H Wang… - American journal of …, 2016 - ncbi.nlm.nih.gov
Accumulating evidence indicates that the lncRNAs play a critical role in cancer progression
and metastasis. In this study, we found that MALAT1 upregulation was associated with larger …
and metastasis. In this study, we found that MALAT1 upregulation was associated with larger …
A computational systems biology approach identifies SLUG as a mediator of partial Epithelial-Mesenchymal Transition (EMT)
Epithelial-mesenchymal plasticity comprises reversible transitions among epithelial, hybrid
epithelial/mesenchymal (E/M) and mesenchymal phenotypes, and underlies various aspects …
epithelial/mesenchymal (E/M) and mesenchymal phenotypes, and underlies various aspects …
Slug, a Stress-Induced Transcription Factor, Stimulates Herpes Simplex Virus 1 Replication and Transactivates a cis-Regulatory Module within the VP16 Promoter
VC Santos, JB Ostler, KS Harrison, C Jones - Journal of Virology, 2023 - Am Soc Microbiol
Stress-mediated activation of the glucocorticoid receptor (GR) and specific stress-induced
transcription factors stimulate herpes simplex virus 1 (HSV-1) productive infection, explant …
transcription factors stimulate herpes simplex virus 1 (HSV-1) productive infection, explant …
Osteopontin (OPN/SPP1), a mediator of tumor progression, is regulated by the mesenchymal transcription factor Slug/SNAI2 in colorectal cancer (CRC)
Simple Summary Expression of the transcription factor Slug/SNAI2 is associated with the
epithelial–mesenchymal transition (EMT) and is correlated with poorer disease-free survival …
epithelial–mesenchymal transition (EMT) and is correlated with poorer disease-free survival …
A computational model of the endothelial to mesenchymal transition
Endothelial cells (ECs) form the lining of lymph and blood vessels. Changes in tissue
requirements or wounds may cause ECs to behave as tip or stalk cells. Alternatively, they …
requirements or wounds may cause ECs to behave as tip or stalk cells. Alternatively, they …
[HTML][HTML] Cross-Talk between the TGF-β and Cell Adhesion Signaling Pathways in Cancer
J Liao, R Chen, B Lin, R Deng, Y Liang… - … Journal of Medical …, 2024 - ncbi.nlm.nih.gov
Transforming growth factor-β (TGF-β) is strongly associated with the cell adhesion signaling
pathway in cell differentiation, migration, etc. Mechanistically, TGF-β is secreted in an …
pathway in cell differentiation, migration, etc. Mechanistically, TGF-β is secreted in an …
Functional balance between Tcf21–Slug defines cellular plasticity and migratory modalities in high grade serous ovarian cancer cell lines
SS Varankar, M More, A Abraham, K Pansare… - …, 2020 - academic.oup.com
Cellular plasticity and transitional phenotypes add to complexities of cancer metastasis that
can be initiated by single cell epithelial to mesenchymal transition (EMT) or cooperative cell …
can be initiated by single cell epithelial to mesenchymal transition (EMT) or cooperative cell …
In Silico Elucidation of the Plausible Inhibitory Potential of Withaferin A of Withania Somnifera Medicinal Herb Against Breast Cancer Targeting Estrogen Receptor
Background: Estrogen Receptors (ER) are members of the nuclear intracellular receptors
family. ER once activated by estrogen, it binds to DNA via translocating into the nucleus and …
family. ER once activated by estrogen, it binds to DNA via translocating into the nucleus and …