Calcium signaling plays an important role in cell survival by influencing mitochondria-related
processes such as energy production and apoptosis. The endoplasmic reticulum (ER) is the …

Cancer cells catabolise nutrients in a different way than healthy cells. Healthy cells mainly
rely on oxidative phosphorylation, while cancer cells employ aerobic glycolysis. Glucose is …

The purpose of this research was to investigate the causes and consequences of pHu
variations in beef cattle. A group of 176 Nellore beef cattle was evaluated and classified into …

Human mitochondrial voltage-dependent anion channel 2 (hVDAC-2), the most
predominant isoform seen in brain mitochondria, is not only crucial for cell survival but is …

Mitochondrial dysfunction was shown to be involved in schizophrenia pathophysiology.
Abnormal energy states can lead to alterations in neural function and thereby to the …

Glycolysis plays a key role in brain energy metabolism. The initial and rate-limiting step of
brain glycolysis is catalyzed mainly by hexokinase I (HKI), the majority of which is bound to …

Hexokinase catalyses the first regulatory step of the glycolytic pathway. We can say without
any exaggeration that both hexokinase and glycolysis are involved in the control of brain …

Several neurological diseases such as bipolar disorders and schizophrenia are linked to
impaired brain energy metabolism. A key feature of brain bioenergetics is hexokinase (HK) …

Two types of binding sites for hexokinase, designated as Type A or Type B sites, have been
shown to coexist on brain mitochondria. The ratio of these sites varies between species …

Métodos de cultivo celular são convenientes na realização de análises funcionais de
alterações/interações protéicas das células neuronais, auxiliando a decifrar o interactoma …