Animal models of osteoarthritis: classification, update, and measurement of outcomes

EL Kuyinu, G Narayanan, LS Nair… - Journal of orthopaedic …, 2016 - Springer
Osteoarthritis (OA) is one of the most commonly occurring forms of arthritis in the world
today. It is a debilitating chronic illness causing pain and immense discomfort to the affected …

Nonhuman primates and translational research: progress, opportunities, and challenges

JD Harding - ILAR journal, 2017 - academic.oup.com
Nonhuman primates (NHPs) are the closest animal models to humans regarding genetics,
physiology and behavior. Therefore, NHPs are usually a critical component in translational …

[图书][B] Rock| water| life: ecology and humanities for a Decolonial South Africa

L Green - 2020 - books.google.com
In Rock| Water| Life Lesley Green examines the interwoven realities of inequality, racism,
colonialism, and environmental destruction in South Africa, calling for environmental …

The comparative genomics and complex population history of Papio baboons

J Rogers, M Raveendran, RA Harris, T Mailund… - Science …, 2019 - science.org
Recent studies suggest that closely related species can accumulate substantial genetic and
phenotypic differences despite ongoing gene flow, thus challenging traditional ideas …

Rhesus macaques as a tractable physiological model of human ageing

KL Chiou, MJ Montague… - … of the Royal …, 2020 - royalsocietypublishing.org
Research in the basic biology of ageing is increasingly identifying mechanisms and
modifiers of ageing in short-lived organisms such as worms and mice. The ultimate goal of …

Neonatal hyperoxia in mice triggers long-term cognitive deficits via impairments in cerebrovascular function and neurogenesis

MA Lithopoulos, X Toussay, S Zhong… - The Journal of …, 2022 - Am Soc Clin Investig
Preterm birth is the leading cause of death in children under 5 years of age. Premature
infants who receive life-saving oxygen therapy often develop bronchopulmonary dysplasia …

[HTML][HTML] Induced pluripotent stem cells throughout the animal kingdom: availability and applications

LV de Figueiredo Pessôa, FF Bressan… - World Journal of Stem …, 2019 - ncbi.nlm.nih.gov
Up until the mid 2000s, the capacity to generate every cell of an organism was exclusive to
embryonic stem cells. In 2006, researchers Takahashi and Yamanaka developed an …

Blood-based miRNA biomarkers as correlates of brain-based miRNA expression

MZ Kos, S Puppala, D Cruz, JL Neary… - Frontiers in Molecular …, 2022 - frontiersin.org
The use of easily accessible peripheral samples, such as blood or saliva, to investigate
neurological and neuropsychiatric disorders is well-established in genetic and epigenetic …

Primate fetal hepatic responses to maternal obesity: epigenetic signalling pathways and lipid accumulation

S Puppala, C Li, JP Glenn, R Saxena… - The Journal of …, 2018 - Wiley Online Library
Key points Maternal obesity (MO) and exposure to a high‐fat, high‐simple‐carbohydrate diet
during pregnancy predisposes offspring to obesity, metabolic and cardiovascular disorders …

[HTML][HTML] Advantages of nonhuman primates as preclinical models for evaluating stem cell-based therapies for Parkinson's disease

DA Grow, JR McCarrey, CS Navara - Stem cell research, 2016 - Elsevier
The derivation of dopaminergic neurons from induced pluripotent stem cells brings new
hope for a patient-specific, stem cell-based replacement therapy to treat Parkinson's disease …