Macroautophagy/autophagy is a cellular catabolic process that results in lysosome-
mediated recycling of organelles and protein aggregates, as well as the destruction of …

Abstract Interleukin-12 (IL-12) and interleukin-23 (IL-23), which belong to the IL-12 family of
cytokines, have a key role in intestinal homeostasis and inflammation and are implicated in …

Inflammatory bowel diseases (IBDs) are chronic disorders of the gastrointestinal tract with
the following two subtypes: Crohn's disease (CD) and ulcerative colitis (UC). To date, most …

Uveitis is a group of diseases characterized by intraocular inflammation, of which some are
driven by autoinflammatory or autoimmune responses, such as Vogt-Koyanagi-Harada …

Although Crohn's disease (CD) and ulcerative colitis (UC) have been considered as
disorders that affect individuals of European ancestry, the epidemiology of the inflammatory …

Inflammatory bowel disease (IBD) represents chronic recurrent intestinal inflammation
resulting from various factors. Crohn's disease (CD) and ulcerative colitis (UC) have been …

Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal
tract, thought to at least in part reflect an aberrant immune response to gut bacteria. IBD is …

Inflammatory bowel disease (IBD) defines a spectrum of complex disorders. Understanding
how environmental risk factors, alterations of the intestinal microbiota, and polygenetic and …

Abstract The cytokines interleukin-12 (IL-12) and IL-23 share a common IL-12/IL-23p40
subunit in structure and play a central role in T cell-mediated responses in inflammation …

Background and Aims Polygenic risk scores (PRS) may soon be used to predict
inflammatory bowel disease (IBD) risk in prevention efforts. We leveraged exome-sequence …