How autophagy controls the intestinal epithelial barrier

EG Foerster, T Mukherjee, L Cabral-Fernandes… - Autophagy, 2022 - Taylor & Francis
Macroautophagy/autophagy is a cellular catabolic process that results in lysosome-
mediated recycling of organelles and protein aggregates, as well as the destruction of …

Activation of the interleukin-23/interleukin-17 signalling pathway in autoinflammatory and autoimmune uveitis

Z Zhong, G Su, A Kijlstra, P Yang - Progress in retinal and eye research, 2021 - Elsevier
Uveitis is a group of diseases characterized by intraocular inflammation, of which some are
driven by autoinflammatory or autoimmune responses, such as Vogt-Koyanagi-Harada …

Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries

Z Liu, R Liu, H Gao, S Jung, X Gao, R Sun, X Liu… - Nature Genetics, 2023 - nature.com
Genetic architecture of the inflammatory bowel diseases across East Asian and European
ancestries | Nature Genetics Skip to main content Thank you for visiting nature.com. You are using …

Effects of race and ethnicity on diagnosis and management of inflammatory bowel diseases

EL Barnes, EV Loftus Jr, MD Kappelman - Gastroenterology, 2021 - Elsevier
Although Crohn's disease (CD) and ulcerative colitis (UC) have been considered as
disorders that affect individuals of European ancestry, the epidemiology of the inflammatory …

[HTML][HTML] Natural anti-inflammatory compounds as drug candidates for inflammatory bowel disease

L Duan, S Cheng, L Li, Y Liu, D Wang… - Frontiers in …, 2021 - frontiersin.org
Inflammatory bowel disease (IBD) represents chronic recurrent intestinal inflammation
resulting from various factors. Crohn's disease (CD) and ulcerative colitis (UC) have been …

Translating immunology into therapeutic concepts for inflammatory bowel disease

HH Uhlig, F Powrie - Annual review of immunology, 2018 - annualreviews.org
Inflammatory bowel disease (IBD) defines a spectrum of complex disorders. Understanding
how environmental risk factors, alterations of the intestinal microbiota, and polygenetic and …

Inflammatory bowel disease and immunonutrition: novel therapeutic approaches through modulation of diet and the gut microbiome

LS Celiberto, FA Graef, GR Healey, ES Bosman… - …, 2018 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal
tract, thought to at least in part reflect an aberrant immune response to gut bacteria. IBD is …

Genome‐wide association studies in Crohn's disease: past, present and future

B Verstockt, KGC Smith, JC Lee - Clinical & translational …, 2018 - Wiley Online Library
Over the course of the past decade, genome‐wide association studies (GWAS) have
revolutionised our understanding of complex disease genetics. One of the diseases that has …

[HTML][HTML] Clinical genomics in inflammatory bowel disease

HH Uhlig, AM Muise - Trends in Genetics, 2017 - cell.com
Genomic technologies inform the complex genetic basis of polygenic inflammatory bowel
disease (IBD) as well as Mendelian disease-associated IBD. Aiming to diagnose patients …

Trans-ancestry, Bayesian meta-analysis discovers 20 novel risk loci for inflammatory bowel disease in an African American, East Asian and European cohort

RY Cordero, JB Cordero, AB Stiemke… - Human molecular …, 2023 - academic.oup.com
Inflammatory bowel disease (IBD) is an immune-mediated chronic intestinal disorder with
major phenotypes: ulcerative colitis (UC) and Crohn's disease (CD). Multiple studies have …