Chemical mixtures in the EU population: composition and potential risks

S Socianu, SK Bopp, E Govarts, L Gilles… - International journal of …, 2022 - mdpi.com
Regulating chemical mixtures is a complex scientific and policy task. The aim of this study
was to investigate typical mixtures and their potential risks based on internal exposure levels …

[HTML][HTML] Internal exposure of Flemish teenagers to environmental pollutants: Results of the Flemish Environment and Health Study 2016–2020 (FLEHS IV)

G Schoeters, VJ Verheyen, A Colles, S Remy… - International Journal of …, 2022 - Elsevier
Abstract The Flemish Environment and Health Study (FLEHS) collects information on
internal exposure to a broad range of environmental chemicals in the general population in …

[HTML][HTML] Evaluation of human biomonitoring data in a health risk based context: An updated analysis of population level data from the Canadian Health Measures …

S Faure, N Noisel, K Werry, S Karthikeyan… - International journal of …, 2020 - Elsevier
In order to characterize exposure of the Canadian population to environmental chemicals, a
human biomonitoring component has been included in the Canadian Health Measures …

Evaluation of chlorpyrifos toxicity through a 28-day study: Cholinesterase activity, oxidative stress responses, parent compound/metabolite levels, and primary DNA …

N Kopjar, S Žunec, G Mendaš, V Micek… - Chemico-Biological …, 2018 - Elsevier
In this 28 day-study, we evaluated the effects of the insecticide chlorpyrifos orally
administered to Wistar rats at doses 0.160, 0.015, and 0.010 mg/kg bw/day. Following …

[HTML][HTML] Pesticide exposure in New Zealand school-aged children: Urinary concentrations of biomarkers and assessment of determinants

Y Li, X Wang, JF McKenzie, A Mannetje, S Cheng… - Environment …, 2022 - Elsevier
This study aimed to assess pesticide exposure and its determinants in children aged 5–14
years. Urine samples (n= 953) were collected from 501 participating children living in urban …

Single or combined exposure to chlorpyrifos and cypermethrin provoke oxidative stress and downregulation in monoamine oxidase and acetylcholinesterase gene …

K Abd El-Moneim Ibrahim… - … Science and Pollution …, 2020 - Springer
The extensive uses of organophosphates and pyrethroids have made it necessary to
investigate the neurotoxicity of their combination as they may implicate in the …

Improving the risk assessment of pesticides through the integration of human biomonitoring and food monitoring data: A case study for chlorpyrifos

JV Tarazona, MDC González-Caballero… - Toxics, 2022 - mdpi.com
The risk assessment of pesticide residues in food is a key priority in the area of food safety.
Most jurisdictions have implemented pre-marketing authorization processes, which are …

[HTML][HTML] Finding synergies for 3Rs–Toxicokinetics and read-across: Report from an EPAA partners' Forum

C Laroche, M Aggarwal, H Bender, P Benndorf… - Regulatory Toxicology …, 2018 - Elsevier
Abstract The European Partnership for Alternative Approaches to Animal Testing (EPAA)
convened a Partners' Forum Toxicokinetics and Read-Across to provide an overview on …

Quercetin attenuates the oxidative injury–mediated upregulation of apoptotic gene expression and catecholaminergic neurotransmitters of the fetal rats' brain following …

KA Ibrahim, M Eleyan, HA Abd El-Rahman… - Neurotoxicity …, 2020 - Springer
The association between gestational exposure to organophosphate and
neurodevelopmental deficits is an area of particular interest, since the developing brain is …

Chronic Exposure to Chlorpyrifos Damages Thyroid Activity and Imbalances Hepatic Thyroid Hormones Signaling and Glucose Metabolism: Dependency of T3 …

T Peluso, V Nittoli, C Reale, I Porreca, F Russo… - International Journal of …, 2023 - mdpi.com
Early life exposure to Endocrine Disruptor Chemicals (EDCs), such as the organophosphate
pesticide Chlorpyrifos (CPF), affects the thyroid activity and dependent process, including …