The treatment of cancer was revolutionized within the last two decades by utilizing the
mechanism of the immune system against malignant tissue in so-called cancer …

Digestive tract cancers (DTC) belong to the most investigated family of tumors. The
incidence, prevalence, and mortality rate of DTC remain high, especially for patients with …

Chimeric antigen receptor (CAR) T-cells represent a new genetically engineered cell-based
immunotherapy tool against cancer. The use of CAR T-cells has revolutionized the …

T cells play a crucial role in the regulation of immune response and are integral to the
efficacy of cancer immunotherapy. Because immunotherapy has emerged as a promising …

Simple Summary Cancer accounts for an increasing number of deaths year on year.
However, new immune-based therapies offer promise in the quest to address this unmet …

Autologous chimeric antigen receptor T‐cell (CAR‐T) therapies have garnered
unprecedented clinical success with multiple regulatory approvals for the treatment of …

Immunotherapy has changed the cancer treatment scenario and revolutionized tumor
immunology. Immunotherapy treatments, such as adoptive T-cell therapy (ACT) or the use of …