Cytochalasans and their impact on actin filament remodeling

C Lambert, K Schmidt, M Karger, M Stadler… - Biomolecules, 2023 - mdpi.com
The eukaryotic actin cytoskeleton comprises the protein itself in its monomeric and
filamentous forms, G-and F-actin, as well as multiple interaction partners (actin-binding …

Early and late phases of liver sinusoidal endothelial cell (LSEC) defenestration in mouse model of systemic inflammation

I Czyzynska-Cichon, J Kotlinowski… - Cellular & Molecular …, 2024 - Springer
Background Liver sinusoidal endothelial cells (LSECs) have transcellular pores, called
fenestrations, participating in the bidirectional transport between the vascular system and …

[HTML][HTML] Protein disulfide isomerase A1 regulates fenestration dynamics in primary mouse liver sinusoidal endothelial cells (LSECs)

I Czyzynska-Cichon, M Giergiel, G Kwiatkowski… - Redox Biology, 2024 - Elsevier
Protein disulfide isomerases (PDIs) are involved in many intracellular and extracellular
processes, including cell adhesion and cytoskeletal reorganisation, but their contribution to …

[HTML][HTML] ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells

L Wang, L He, W Yi, M Wang, F Xu, H Liu, J Nie… - Iscience, 2024 - cell.com
Liver sinusoidal endothelial cells (LSECs) have a unique morphological structure known as"
fenestra" that plays a crucial role in liver substance exchange and homeostasis …

Tubulin-Targeted Therapy in Melanoma Increases the Cell Migration Potential by Activation of the Actomyosin Cytoskeleton─ An In Vitro Study

M Luty, R Szydlak, J Pabijan, J Zemła… - ACS Biomaterials …, 2024 - ACS Publications
One of the most dangerous aspects of cancers is their ability to metastasize, which is the
leading cause of death. Hence, it holds significance to develop therapies targeting the …

Mouse liver sinusoidal endothelial cell responses to the glucocorticoid receptor agonist dexamethasone

S Bhandari, I Kyrrestad, J Simón-Santamaría… - Frontiers in …, 2024 - frontiersin.org
Liver sinusoidal endothelial cells (LSECs) which make up the fenestrated wall of the hepatic
sinusoids, are active scavenger cells involved in blood waste clearance and liver immune …

Correlative Super‐Resolution Imaging of Cellular Nanopores Facilitated by Transparent Polymer Waveguide Chips

SB Dutta, JC Schürstedt‐Seher… - Advanced Optical …, 2024 - Wiley Online Library
Super‐resolution optical microscopy (SRM) permits the visualization of subcellular
structures of biological samples beyond the diffraction limit of light. To evaluate and utilize …

Proteomic Analysis of Dysfunctional Liver Sinusoidal Endothelial Cells Reveals Substantial Differences in Most Common Experimental Models of Chronic Liver …

M Gil, M Azkargorta, C Fuster… - International Journal of …, 2023 - mdpi.com
Molecular markers of dedifferentiation of dysfunctional liver sinusoidal endothelial cells
(LSEC) have not been fully elucidated. We aimed at deciphering the molecular profile of …

Multi-Cellular Network Model Predicts Alterations in Glomerular Endothelial Structure in Diabetic Kidney Disease

K Patidar, AN Ford Versypt - bioRxiv, 2024 - biorxiv.org
Diabetic kidney disease (DKD) progression is often marked by early glomerular endothelial
cell (GEC) dysfunction, including alterations in the fenestration size and number linked to …

Tubulin-Targeted Therapy in Melanoma Increases Cell Invasive Potential by Activation of Actomyosin Cytoskeleton-an in vitro study

M Luty, R Szydlak, J Pabijan, J Zemla, IH Oevreeide… - bioRxiv, 2024 - biorxiv.org
One of the most dangerous aspects of cancers is their ability to metastasize, which is the
leading cause of death. Hence, it holds significance to develop therapies targeting the …