The aim of the present systematic review and meta-analysis was to assess the effect of the
different therapeutic options for repeated embryo implantation failure (RIF) on a subsequent …

Recurrent implantation failure (RIF) is an iatrogenic condition, being the result of repetitive
unsuccessful cycles of IVF or intracytoplasmic sperm injection (ICSI) treatment. The aim of …

STUDY QUESTION How should recurrent implantation failure (RIF) in patients undergoing
ART be defined and managed? SUMMARY ANSWER This is the first ESHRE good practice …

BACKGROUND Assisted hatching (AH) is a manipulation of zona pellucida aiming to
facilitate embryo implantation. METHODS Systematic review and meta-analysis of medical …

Background Failure of implantation and conception may result from inability of the blastocyst
to escape from its outer coat, which is known as the zona pellucida. Artificial disruption of …

Abstract The World Health Organization estimates that one in six couples experience some
delay in conception and an increasing number require treatment by the assisted conception …

Chromosomal abnormalities, sperm DNA damage, zona hardening, inadequate culture
conditions, and suboptimal embryo development all play a significant role in the etiology of …

In the last decades, to enhance success rates in assisted reproductive technology (ART)
cycles, scientists have continually tried to optimize embryo culture and selection to increase …

There is good evidence that assisted hatching (AH) slightly improves clinical pregnancy
rates, particularly in poor prognosis patients, including those with prior failed in vitro …

Zona pellucida (ZP) manipulation, termed “assisted hatching”(AH), has been introduced in
order to favor embryo hatching and ultimately improve assisted reproductive technology …