Visible-to-NIR-light activated release: from small molecules to nanomaterials

R Weinstain, T Slanina, D Kand, P Klan - Chemical reviews, 2020 - ACS Publications
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

meso-Methyl BODIPY Photocages: Mechanisms, Photochemical Properties, and Applications

P Shrestha, D Kand, R Weinstain… - Journal of the American …, 2023 - ACS Publications
meso-methyl BODIPY photocages have recently emerged as an exciting new class of
photoremovable protecting groups (PPGs) that release leaving groups upon absorption of …

Taking phototherapeutics from concept to clinical launch

BM Vickerman, EM Zywot, TK Tarrant… - Nature Reviews …, 2021 - nature.com
More than four decades have passed since the first example of a light-activated (caged)
compound was described. In the intervening years, a large number of light-responsive …

[HTML][HTML] Intelligent polymeric hydrogen sulfide delivery systems for therapeutic applications

F Rong, T Wang, Q Zhou, H Peng, J Yang, Q Fan, P Li - Bioactive Materials, 2023 - Elsevier
Hydrogen sulfide (H 2 S) plays an important role in regulating various pathological
processes such as protecting mammalian cell from harmful injuries, promoting tissue …

Recent advances in self-immolative linkers and their applications in polymeric reporting systems

AG Gavriel, MR Sambrook, AT Russell, W Hayes - Polymer Chemistry, 2022 - pubs.rsc.org
Interest in self-immolative chemistry has grown over the past decade with more research
groups harnessing the versatility to control the release of a compound from a larger …

Progress and perspective on hydrogen sulfide donors and their biomedical applications

ZL Song, L Zhao, T Ma, A Osama… - Medicinal Research …, 2022 - Wiley Online Library
Following the discovery of nitric oxide (NO) and carbon monoxide (CO), hydrogen sulfide
(H2S) has been identified as the third gasotransmitter in humans. Increasing evidence have …

Photo-controllable biochemistry: Exploiting the photocages in phototherapeutic window

H Xiong, Y Xu, B Kim, H Rha, B Zhang, M Li, GF Yang… - Chem, 2023 - cell.com
Photochemical tools have revolutionized the landscape of biomedicine, enabling the
exploration of nature in a noninvasively remote-controlled manner. Among them, especially …

Spatiotemporal control of biology: Synthetic photochemistry toolbox with far-red and near-infrared light

S Jia, EM Sletten - ACS chemical biology, 2021 - ACS Publications
The complex network of naturally occurring biological pathways motivates the development
of new synthetic molecules to perturb and/or detect these processes for fundamental …

Development and Application of Carbonyl Sulfide-Based Donors for H2S Delivery

CM Levinn, MM Cerda, MD Pluth - Accounts of chemical research, 2019 - ACS Publications
Conspectus In addition to nitric oxide and carbon monoxide, hydrogen sulfide (H2S) has
been recently recognized as an important biological signaling molecule with implications in …

External stimuli-responsive gasotransmitter prodrugs: Chemistry and spatiotemporal release

X Ji, Z Zhong - Journal of Controlled Release, 2022 - Elsevier
Gasotransmitters like nitric oxide, carbon monoxide, and hydrogen sulfide with unique
pleiotropic pharmacological effects in mammals are an emerging therapeutic modality for …