Epigenetic signatures in gastric cancer: current knowledge and future perspectives
F Sogutlu, M Pekerbas, C Biray Avci - Expert Review of Molecular …, 2022 - Taylor & Francis
Introduction Gastric cancer (GC) is the fifth most common malignancy in the world and
accounts for 7.7% of all cancer-related deaths. Early diagnosis of GC is critical in terms of …
accounts for 7.7% of all cancer-related deaths. Early diagnosis of GC is critical in terms of …
Targeting emerging cancer hallmarks by transition metal complexes: Epigenetic reprogramming and epitherapies. Part II
J Arakelyan, DA Rusanov, MR Chang… - Coordination Chemistry …, 2023 - Elsevier
In this last decade, our understanding of the complex factors and processes that drive
cancer development and progression has broadened in scope and grown in depth. Today, it …
cancer development and progression has broadened in scope and grown in depth. Today, it …
[HTML][HTML] PAX9 reactivation by inhibiting DNA methyltransferase triggers antitumor effect in oral squamous cell carcinoma
CS Bhol, SR Mishra, S Patil, SK Sahu, R Kirtana… - … Et Biophysica Acta (BBA …, 2022 - Elsevier
Aberrant DNA hypermethylation is associated with oral carcinogenesis. Procaine, a local
anesthetic, is a DNA methyltransferase (DNMT) inhibitor that activates anticancer …
anesthetic, is a DNA methyltransferase (DNMT) inhibitor that activates anticancer …
Palladium (II) complexes bearing N, O-bidentate Schiff base ligands: Experimental, in-silico, antibacterial, and catalytic properties
Two N, O-bidentate ligands (1, 2), and their Pd (II) complexes,(1a, 2a) were synthesized and
characterized via elemental analysis, IR, 1 H and 13 C NMR, magnetic moment and UV …
characterized via elemental analysis, IR, 1 H and 13 C NMR, magnetic moment and UV …
Targeting DNA methyltransferases for cancer therapy
K Wang, Z He, G Jin, S Jin, Y Du, S Yuan, J Zhang - Bioorganic Chemistry, 2024 - Elsevier
DNA methyltransferases (DNMTs) play a crucial role in genomic DNA methylation. In
mammals, DNMTs regulate the dynamic patterns of DNA methylation in embryonic and adult …
mammals, DNMTs regulate the dynamic patterns of DNA methylation in embryonic and adult …
Biological Evaluation of 2-(3, 4-dihydroxyphenyl)-4-((4-methoxyphenyl) imino)-4H-chromene-3, 5, 7-triol: Design, Synthesis, and Molecular Docking Studies
D Sangeetha - Biocatalysis and Agricultural Biotechnology, 2024 - Elsevier
Plant materials are known to contain a category of naturally occurring compounds referred to
as flavonoids. Quercetin is classified as a flavonol, which is present in various parts of plants …
as flavonoids. Quercetin is classified as a flavonol, which is present in various parts of plants …
[PDF][PDF] Some heterocyclic hydrazone compounds: Synthesis, spectral characterization and anticancer activity study
Cancer is currently ongoing to be a significant health problem threatening human health.
Hydrazone compounds constitute a popular class of organic compounds used in novel drug …
Hydrazone compounds constitute a popular class of organic compounds used in novel drug …
Investigation of the effects of zinc oxide nanoparticles synthesized by Saccharomyces cerevisiae aqueous lysate on in-vitro wound healing model
Amaç: Bu çalışmanın amacı hamur mayası (Saccharomyces cerevisiae) sulu lizatı ile
sentezlenen çinko oksit nanopartiküllerinin (ZnONPs) L929 fare fibroblast hücreleri …
sentezlenen çinko oksit nanopartiküllerinin (ZnONPs) L929 fare fibroblast hücreleri …
[PDF][PDF] Raloxifene-loaded and aptamer-bonded exosomes induce autophagic and apoptotic death in HeLa cells by enhancing the lysosomotropic effect
Raloxifene-loaded and aptamer-bonded exosomes induce autophagic and apoptotic death in
HeLa cells by enhancing the lysosomotropi Page 1 Raloxifene-loaded and aptamer-bonded …
HeLa cells by enhancing the lysosomotropi Page 1 Raloxifene-loaded and aptamer-bonded …
Crystal structure, DFT studies, in silico evaluation of as a potential inhibitor against monkeypox virus, and ADMET properties of tetrachlorometallate salts of procaine
Two novel tetrachlorometallate salts of procaine have been designed and evaluated as
potential antiviral drug candidates. Bis (procainium) tetrachlorido cadmium (II)(Complex 1) …
potential antiviral drug candidates. Bis (procainium) tetrachlorido cadmium (II)(Complex 1) …