KISS1 metastasis suppressor in tumor dormancy: a potential therapeutic target for metastatic cancers?

S Harihar, DR Welch - Cancer and Metastasis Reviews, 2023 - Springer
Present therapeutic approaches do not effectively target metastatic cancers, often limited by
their inability to eliminate already-seeded non-proliferative, growth-arrested, or therapy …

Hallmarks of cancer resistance

M Tufail, JJ Hu, J Liang, CY He, WD Wan, YQ Huang… - Iscience, 2024 - cell.com
This review explores the hallmarks of cancer resistance, including drug efflux mediated by
ATP-binding cassette (ABC) transporters, metabolic reprogramming characterized by the …

Zika virus E protein dysregulate mir-204/WNT2 signalling in human fetal neural stem cells

R Bhagat, P Rajpara, G Kaur, K Gupta, P Seth - Brain Research Bulletin, 2021 - Elsevier
Zika Virus (ZIKV) belongs to the family of flaviviruses, and is neurotrophic. It has been known
to cause severe congenital disabilities including microcephaly in neonates. The virus has a …

Bioactive Phytochemicals from Castor (Ricinus communis Linneo) Seed Oil Processing By-products

N Cheikhyoussef, A Cheikhyoussef - Bioactive Phytochemicals from …, 2023 - Springer
Abstract Castor (Ricinus communis Linneo) belongs to the plant family of Euphorbiaceae
and is a crop intensively cultivated to produce oil from its seeds. There is a high demand of …

Canonical WNT/β-catenin signaling upregulates aerobic glycolysis in diverse cancer types

M Rathee, SM Umar, AJR Dev, A Kashyap… - Molecular Biology …, 2024 - Springer
Despite many efforts, a comprehensive understanding and clarification of the intricate
connections within cancer cell metabolism remain elusive. This might pertain to intracellular …

Targeting oncogenic WNT signalling with WNT signalling-derived peptides

V Yadav, N Jobe, L Mehdawi, T Andersson - Pharmacology of the WNT …, 2021 - Springer
WNT signalling is known to be a crucial regulator of embryonic development and tissue
homeostasis. Aberrant expression of WNT signalling elements or their mutations has been …

A unique cell population expressing the Epithelial-Mesenchymal Transition-transcription factor Snail moderates microglial and astrocyte injury responses

C Clarkson-Paredes, MT Karl, A Popratiloff… - PNAS nexus, 2023 - academic.oup.com
Insults to the central nervous system (CNS) elicit common glial responses including
microglial activation evidenced by functional, morphological, and phenotypic changes, as …