During the last decades, there has been an increased interest in the discovery and
validation of biomarkers that reliably reflect specific aspects of lupus. Although many …

In the years of personalized (or precision) medicine the 'omics' methodologies in biomedical
sciences—genomics, transcriptomics, proteomics and metabolomics—are helping …

Lupus nephritis (LN) is a pathologically heterogenous autoimmune disease linked to end-
stage kidney disease and mortality. Better therapeutic strategies are needed as only 30 …

Системная красная волчанка (СКВ)-системное аутоиммунное ревматическое
заболевание неизвестной этиологии, характеризующееся гиперпродукцией …

The mitochondrion supplies energy to the cell and regulates apoptosis. Unlike other
mammalian organelles, mitochondria are formed by binary fission and cannot be directly …

Systemic lupus erythematosus (SLE) is a representative systemic autoimmune disease that
has various types of manifestations in multiple organs. Additionally, SLE is one of the most …

Systemic lupus erythematosus (SLE) is an autoimmune disorder with a wide range of clinical
symptoms. Enormous progress has been made in the immunological and genetic …

Objective Systemic lupus erythematosus (SLE) is a clinically and biologically heterogenous
autoimmune disease. We aimed to investigate the plasma proteome of patients with active …

Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease
characterized by autoantibodies directed against numerous self-nuclear antigens. Because …

Background Lupus nephritis (LN) occurs in< 40% of patients with SLE. Reliable biomarkers
of kidney damage are needed to identify patients with SLE at risk of developing LN to …