Signaling pathways governing glioma cancer stem cells behavior
A Nasrolahi, S Azizidoost, K Radoszkiewicz, S Najafi… - Cellular …, 2023 - Elsevier
Glioma is the most common malignant brain tumor that develops in the glial tissue. Several
studies have identified that glioma cancer stem cells (GCSCs) play important roles in tumor …
studies have identified that glioma cancer stem cells (GCSCs) play important roles in tumor …
Poly (ADP-ribose) polymerase 1 and neurodegenerative diseases: Past, present, and future
ML Hu, YR Pan, YY Yong, Y Liu, L Yu, DL Qin… - Ageing research …, 2023 - Elsevier
Abstract Poly (ADP-ribose) polymerase 1 (PARP1) is a first responder that recognizes DNA
damage and facilitates its repair. Neurodegenerative diseases, characterized by progressive …
damage and facilitates its repair. Neurodegenerative diseases, characterized by progressive …
DNA damage response inhibitors enhance tumour treating fields (TTFields) potency in glioma stem-like cells
A Vanderlinden, CG Jones, KN Myers… - British Journal of …, 2023 - nature.com
Background High-grade gliomas are primary brain cancers with unacceptably low and
persistent survival rates of 10–16 months for WHO grade 4 gliomas over the last 40 years …
persistent survival rates of 10–16 months for WHO grade 4 gliomas over the last 40 years …
PDIA3P1 promotes Temozolomide resistance in glioblastoma by inhibiting C/EBPβ degradation to facilitate proneural-to-mesenchymal transition
Z Gao, J Xu, Y Fan, Y Qi, S Wang, S Zhao… - Journal of Experimental …, 2022 - Springer
Background Resistance to temozolomide (TMZ) is a major obstacle to preventing
glioblastoma (GBM) recurrence after surgery. Although long noncoding RNAs (lncRNAs) …
glioblastoma (GBM) recurrence after surgery. Although long noncoding RNAs (lncRNAs) …
Molecular landscapes of glioblastoma cell lines revealed a group of patients that do not benefit from WWOX tumor suppressor expression
Ż Kałuzińska-Kołat, D Kołat, K Kośla… - Frontiers in …, 2023 - frontiersin.org
Introduction Glioblastoma (GBM) is notorious for its clinical and molecular heterogeneity,
contributing to therapeutic failure and a grim prognosis. WWOX is one of the tumor …
contributing to therapeutic failure and a grim prognosis. WWOX is one of the tumor …
A novel approach to investigate the combinatorial effects of TLK1 (Tousled-Like Kinase1) inhibitors with Temozolomide for glioblastoma therapy
B Priya, D Chhabria, JM Dhongdi, S Kirubakaran - Bioorganic Chemistry, 2024 - Elsevier
Glioblastoma multiforme (GBM) is an aggressive, incurable brain tumor with poor prognosis
and limited treatment options. Temozolomide (TMZ) is the standard chemotherapeutic …
and limited treatment options. Temozolomide (TMZ) is the standard chemotherapeutic …
ERCC1 overexpression increases radioresistance in colorectal cancer cells
YJ Huang, MY Huang, TL Cheng, SH Kuo, CC Ke… - Cancers, 2022 - mdpi.com
Simple Summary The 20–30% of locally advanced rectal cancer patients undergoing
preoperative concurrent chemoradiotherapy had no expected efficacy, and ERCC1 …
preoperative concurrent chemoradiotherapy had no expected efficacy, and ERCC1 …
[HTML][HTML] Design of Experiments to Tailor the Potential of BSA-Coated Peptide Nanocomplexes for Temozolomide/p53 Gene Co-Delivery
I Afonso, AR Neves, D Eusébio, T Albuquerque… - Pharmaceutics, 2024 - mdpi.com
Background: Gene therapy can be viewed as a promising/valuable therapeutic approach
directed to cancer treatment, including glioblastoma. Concretely, the combination of gene …
directed to cancer treatment, including glioblastoma. Concretely, the combination of gene …
New perspective on DNA response pathway (DDR) in glioblastoma, focus on classic biomarkers and emerging roles of ncRNAs
Background Glioblastoma (GBM) is the most frequent type of primary brain cancer, having a
median survival of only 15 months. The current standard of care includes a combination of …
median survival of only 15 months. The current standard of care includes a combination of …
Methylcellulose/agarose hydrogel loaded with short electrospun PLLA/laminin fibers as an injectable scaffold for tissue engineering/3D cell culture model for tumour …
This research aimed at designing and fabricating a smart thermosensitive injectable
methylcellulose/agarose hydrogel system loaded with short electrospun bioactive …
methylcellulose/agarose hydrogel system loaded with short electrospun bioactive …