Preoperative acute lung injury and oxygenation impairment occurred in the patients with acute aortic dissection

X Zhao, M Bie - BMC Cardiovascular Disorders, 2022 - Springer
Acute lung injury (ALI) and oxygenation impairment (OI) frequently occur in the patients with
acute aortic dissection (AAD), which may necessitate mechanical ventilation and result in …

[HTML][HTML] miR-27a regulates vascular remodeling by targeting endothelial cells' apoptosis and interaction with vascular smooth muscle cells in aortic dissection

Y Sun, YU Xiao, H Sun, Z Zhao, J Zhu, L Zhang… - Theranostics, 2019 - ncbi.nlm.nih.gov
Rationale: Aortic dissection (AD) is caused by functional disorder of cells in the aortic wall,
which is largely attributed to vascular remodeling. Therapeutic strategies for AD remain …

Differential expression profile of plasma exosomal microRNAs in acute type A aortic dissection with acute lung injury

C Zhang, H Bai, L Zhang, Y Zhang, X Chen, R Shi… - Scientific Reports, 2022 - nature.com
MicroRNAs (miRNAs) packaged into exosomes mediate cell communication and contribute
to the pathogenesis of acute type A aortic dissection (ATAAD) with acute lung injury (ALI) …

Perioperative oxygenation impairment related to type a aortic dissection

Q Liu, Y Guan, X Yang, Y Jiang, F Hei - Perfusion, 2024 - journals.sagepub.com
Type A aortic dissection (TAAD) is a life-threatening disease with high mortality and poor
prognosis, usually treated by surgery. There are many complications in its perioperative …

[HTML][HTML] Preoperative hypoxemia in patients with type A acute aortic dissection: a retrospective study on incidence, related factors and clinical significance

Z Guo, Y Yang, M Zhao, B Zhang, J Lu… - Journal of Thoracic …, 2019 - ncbi.nlm.nih.gov
Background Pre-operative hypoxemia (HO) is a serious complication occurring in acute type
A aortic dissection (AAD) patients. Methods This was a retrospective study of 505 patients …

Angiotensin II induces apoptosis of cardiac microvascular endothelial cells via regulating PTP1B/PI3K/Akt pathway

Y Wang, Y Fan, Y Song, X Han, M Fu, J Wang… - In Vitro Cellular & …, 2019 - Springer
Endothelial cell apoptosis and renin-angiotensin-aldosterone system (RAAS) activation are
the major pathological mechanisms for cardiovascular disease and heart failure; however …

[HTML][HTML] MiR-15a-5p accelerated vascular smooth muscle cells viabilities and migratory abilities via targeting Bcl-2

P Hui, W Jianhua, LI Shaohui - Physiological Research, 2022 - ncbi.nlm.nih.gov
Aortic dissection (AD) caused by the tear in the aortic wall threatens aorta, causing severe
chest pain, syncope and even death. Fortunately, development of genetic technology …

Beneficial effect of the mitochondrial ATP‑sensitive potassium channel‑specific opener nicorandil on the collapsed lung via inhibition of apoptosis in clinical thoracic …

C Wang, Z Wu, Z Li, Z Wang… - Molecular Medicine …, 2023 - spandidos-publications.com
With the use of thoracoscopic surgery technology, one‑lung ventilation (OLV) is becoming
more crucial as a basic requirement for enhanced recovery after surgery; however, it can …

Interleukin 22 attenuated angiotensin II induced acute lung injury through inhibiting the apoptosis of pulmonary microvascular endothelial cells

Z Wu, Z Hu, X Cai, W Ren, F Dai, H Liu, J Chang… - Scientific reports, 2017 - nature.com
Apoptosis of pulmonary microvascular endothelial cells (PMVECs) was considered to be
closely related to the pathogenesis of acute lung injury (ALI). We aim to investigate whether …

Dephosphorylation of Y685‐VE‐Cadherin Involved in Pulmonary Microvascular Endothelial Barrier Injury Induced by Angiotensin II

Z Wu, Z Wang, F Dai, H Liu, W Ren… - Mediators of …, 2016 - Wiley Online Library
Angiotensin II (AngII) caused pulmonary microvascular endothelial barrier injury, which
induced acute aortic dissection (AAD) combined with acute lung injury (ALI). However, the …