Epigenetic regulatory mechanisms, including DNA methylation, histone modification,
chromatin remodeling, and microRNA expression, play critical roles in cell differentiation …

The prefrontal cortex (PFC) serves as the chief executive officer of the brain, controlling the
highest level cognitive and emotional processes. Its local circuits among glutamatergic …

These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

INTRODUCTION Chromosomal conformations, topologically associated chromatin domains
(TADs) assembling in nested fashion across hundreds of kilobases, and other “three …

Identification of risk variants for neuropsychiatric diseases within enhancers underscores the
importance of understanding population-level variation in enhancer function in the human …

Large-scale transcriptome studies with multiple samples per individual are widely used to
study disease biology. Yet, current methods for differential expression are inadequate for …

Epigenetic modifications are increasingly recognized to play a role in the etiology and
pathophysiology of schizophrenia and other psychiatric disorders with developmental …

DNA methylation is a critical regulatory mechanism implicated in development, learning,
memory, and disease in the human brain. Here we have elucidated DNA methylation …

Schizophrenia (SCZ) is a debilitating neuropsychiatric disorder with high heritability and
complex inheritance. In the past decade, successful identification of numerous susceptibility …