Hydrogels as drug delivery systems: A review of current characterization and evaluation techniques
Owing to their tunable properties, controllable degradation, and ability to protect labile
drugs, hydrogels are increasingly investigated as local drug delivery systems. However, a …
drugs, hydrogels are increasingly investigated as local drug delivery systems. However, a …
Artificial intelligence as the next step towards precision pathology
Pathology is the cornerstone of cancer care. The need for accuracy in histopathologic
diagnosis of cancer is increasing as personalized cancer therapy requires accurate …
diagnosis of cancer is increasing as personalized cancer therapy requires accurate …
Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer
BACKGROUND. Liquid biopsies have demonstrated that the constitutively active androgen
receptor splice variant-7 (AR-V7) associates with reduced response and overall survival …
receptor splice variant-7 (AR-V7) associates with reduced response and overall survival …
Digital image analysis in breast pathology—from image processing techniques to artificial intelligence
Breast cancer is the most common malignant disease in women worldwide. In recent
decades, earlier diagnosis and better adjuvant therapy have substantially improved patient …
decades, earlier diagnosis and better adjuvant therapy have substantially improved patient …
Different approaches for interpretation and reporting of immunohistochemistry analysis results in the bone tissue–a review
N Fedchenko, J Reifenrath - Diagnostic pathology, 2014 - Springer
Background Immunohistochemistry (IHC) is a well-established, widely accepted method in
both clinical and experimental parts of medical science. It allows receiving valuable …
both clinical and experimental parts of medical science. It allows receiving valuable …
GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer
Triple negative breast cancer (TNBC) is a deadly form of breast cancer due to the
development of resistance to chemotherapy affecting over 30% of patients. New …
development of resistance to chemotherapy affecting over 30% of patients. New …
When tissue antigens and antibodies get along: revisiting the technical aspects of immunohistochemistry—the red, brown, and blue technique
JA Ramos-Vara, MA Miller - Veterinary pathology, 2014 - journals.sagepub.com
Once focused mainly on the characterization of neoplasms, immunohistochemistry (IHC)
today is used in the investigation of a broad range of disease processes with applications in …
today is used in the investigation of a broad range of disease processes with applications in …
[HTML][HTML] Principles and approaches for reproducible scoring of tissue stains in research
DK Meyerholz, AP Beck - Laboratory investigation, 2018 - Elsevier
Abstract Evaluation of tissues is a common and important aspect of translational research
studies. Labeling techniques such as immunohistochemistry can stain cells/tissues to …
studies. Labeling techniques such as immunohistochemistry can stain cells/tissues to …
Unsupervised discovery of tissue architecture in multiplexed imaging
J Kim, S Rustam, JM Mosquera, SH Randell… - Nature …, 2022 - nature.com
Multiplexed imaging and spatial transcriptomics enable highly resolved spatial
characterization of cellular phenotypes, but still largely depend on laborious manual …
characterization of cellular phenotypes, but still largely depend on laborious manual …
The state of the art for artificial intelligence in lung digital pathology
Lung diseases carry a significant burden of morbidity and mortality worldwide. The advent of
digital pathology (DP) and an increase in computational power have led to the development …
digital pathology (DP) and an increase in computational power have led to the development …