Computational identification of tissue-specific splicing regulatory elements in human genes from RNA-Seq data

E Badr, M ElHefnawi, LS Heath - PLoS One, 2016 - journals.plos.org
Alternative splicing is a vital process for regulating gene expression and promoting
proteomic diversity. It plays a key role in tissue-specific expressed genes. This specificity is …

The smallest valid extension-based efficient, rare graph pattern mining, considering length-decreasing support constraints and symmetry characteristics of graphs

U Yun, G Lee, CH Kim - Symmetry, 2016 - mdpi.com
Frequent graph mining has been proposed to find interesting patterns (ie, frequent sub-
graphs) from databases composed of graph transaction data, which can effectively express …

Combinatorial pattern of histone modifications in exon skipping event

W Chen, X Song, H Lin - Frontiers in Genetics, 2019 - frontiersin.org
Histone modifications are associated with alternative splicing. It has been suggested that
histone modifications act in combinational patterns in gene expression regulation. However …

HPC-based parallel algorithms for generating random networks and some other network analysis problems

MM Alam - 2016 - vtechworks.lib.vt.edu
The advancement of modern technologies has resulted in an explosive growth of complex
systems, such as the Internet, biological, social, and various infrastructure networks, which …

Identifying splicing regulatory elements with de Bruijn graphs

E Badr, LS Heath - Journal of Computational Biology, 2014 - liebertpub.com
Splicing regulatory elements (SREs) are short, degenerate sequences on pre-mRNA
molecules that enhance or inhibit the splicing process via the binding of splicing factors …