Chikungunya virus: epidemiology, replication, disease mechanisms, and prospective intervention strategies

LA Silva, TS Dermody - The Journal of clinical investigation, 2017 - Am Soc Clin Investig
Chikungunya virus (CHIKV), a reemerging arbovirus, causes a crippling musculoskeletal
inflammatory disease in humans characterized by fever, polyarthralgia, myalgia, rash, and …

Chikungunya: epidemiology, pathogenesis, clinical features, management, and prevention

F Vairo, N Haider, R Kock, F Ntoumi… - Infectious Disease …, 2019 - id.theclinics.com
Chikungunya (CHIK) is a disabling and debilitating zoonotic disease of humans caused by
the Chikungunya virus (CHIKV), which is transmitted by CHIKV-infected Aedes spp …

Chikungunya: a re-emerging virus

FJ Burt, MS Rolph, NE Rulli, S Mahalingam, MT Heise - The Lancet, 2012 - thelancet.com
In the past decade, chikungunya—a virus transmitted by Aedes spp mosquitoes—has re-
emerged in Africa, southern and southeastern Asia, and the Indian Ocean Islands as the …

[PDF][PDF] Chikungunya virus infection: an overview

C Caglioti, E Lalle, C Castilletti, F Carletti… - New …, 2013 - carivecnet.carpha.org
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus belonging to the
Togaviridae family, first isolated in Tanzania in 1952. The main vectors are mosquitoes from …

Chikungunya fever: an epidemiological review of a re-emerging infectious disease

JE Staples, RF Breiman… - Clinical infectious …, 2009 - academic.oup.com
Chikungunya fever is an acute febrile illness associated with severe, often debilitating
polyarthralgias. The disease is caused by Chikungunya virus (CHIKV), an arthropod-borne …

A virus-like particle vaccine for epidemic Chikungunya virus protects nonhuman primates against infection

W Akahata, ZY Yang, H Andersen, S Sun… - Nature medicine, 2010 - nature.com
Chikungunya virus (CHIKV) has infected millions of people in Africa, Europe and Asia, since
this alphavirus reemerged from Kenya in 2004. The severity of the disease and the spread of …

Safety and tolerability of chikungunya virus-like particle vaccine in healthy adults: a phase 1 dose-escalation trial

LJ Chang, KA Dowd, FH Mendoza, JG Saunders… - The Lancet, 2014 - thelancet.com
Background Chikungunya virus—a mosquito-borne alphavirus—is endemic in Africa and
south and southeast Asia and has recently emerged in the Caribbean. No drugs or vaccines …

Chikungunya virus arthritis in adult wild-type mice

J Gardner, I Anraku, TT Le, T Larcher, L Major… - Journal of …, 2010 - Am Soc Microbiol
Chikungunya virus is a mosquito-borne arthrogenic alphavirus that has recently reemerged
to produce the largest epidemic ever documented for this virus. Here we describe a new …

[HTML][HTML] A scoping review of Chikungunya virus infection: epidemiology, clinical characteristics, viral co-circulation complications, and control

JVJ Silva Jr, LF Ludwig-Begall, EF de Oliveira-Filho… - Acta tropica, 2018 - Elsevier
Chikungunya fever is a mosquito-borne viral illness characterized by a sudden onset of
fever associated with joint pains. It was first described in the 1950s during a Chikungunya …

Development of a highly protective combination monoclonal antibody therapy against Chikungunya virus

P Pal, KA Dowd, JD Brien, MA Edeling… - PLoS …, 2013 - journals.plos.org
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes global
epidemics of a debilitating polyarthritis in humans. As there is a pressing need for the …