Recent advances in the synthesis of β-carboline alkaloids
T Szabó, B Volk, M Milen - Molecules, 2021 - mdpi.com
β-Carboline alkaloids are a remarkable family of natural and synthetic indole-containing
heterocyclic compounds and they are widely distributed in nature. Recently, these alkaloids …
heterocyclic compounds and they are widely distributed in nature. Recently, these alkaloids …
Recent Advances on the Synthesis and Application of Tetrahydro‐β‐Carbolines
Tetrahydro‐β‐carbolines (THβCs) also known as tryptolines serve as important structural
elements in natural products and pharmaceutical compounds, and they are also utilized in …
elements in natural products and pharmaceutical compounds, and they are also utilized in …
An overview on synthetic entries to tetrahydro-β-carbolines
P Maity, D Adhikari, AK Jana - Tetrahedron, 2019 - Elsevier
The tetrahydro-β-carboline (THBC) nucleus is a predominant feature of a vast array of
naturally occurring alkaloids. Most of these alkaloids have been found to exhibit significant …
naturally occurring alkaloids. Most of these alkaloids have been found to exhibit significant …
β-Carboline-based molecular hybrids as anticancer agents: A brief sketch
JP Soni, Y Yeole, N Shankaraiah - RSC Medicinal Chemistry, 2021 - pubs.rsc.org
Cancer is a huge burden on the healthcare system and is foremost cause of mortality across
the globe. Among various therapeutic strategies, chemotherapy plays an enormous role in …
the globe. Among various therapeutic strategies, chemotherapy plays an enormous role in …
Carboline regioisomers based on unified synthetic approaches
ASM Arshad, MN Mordi - Advanced Synthesis & Catalysis, 2023 - Wiley Online Library
Carbolines are a prominent class of tricyclic alkaloids omnipresent in natural products and
bioactive compounds. Four different carboline regioisomers are known (α‐, β‐, γ‐, and δ …
bioactive compounds. Four different carboline regioisomers are known (α‐, β‐, γ‐, and δ …
Synthesis of podophyllotoxin linked β-carboline congeners as potential anticancer agents and DNA topoisomerase II inhibitors
A series of new podophyllotoxin linked β-carboline congeners have been synthesized by
coupling various substituted β-carboline acids with 4β-aminopodophyllotoxin. Evaluation of …
coupling various substituted β-carboline acids with 4β-aminopodophyllotoxin. Evaluation of …
Reusable, homogeneous water soluble photoredox catalyzed oxidative dehydrogenation of N-heterocycles in a biphasic system: application to the synthesis of …
Herein, a simple and efficient method for the oxidative dehydrogenation (ODH) of tetrahydro-
β-carbolines, indolines and tetrahydro-(iso) quinolines is described using a reusable …
β-carbolines, indolines and tetrahydro-(iso) quinolines is described using a reusable …
Design and Synthesis of DNA‐Interactive β‐Carboline–Oxindole Hybrids as Cytotoxic and Apoptosis‐Inducing Agents
A new series of (E)‐3‐[(1‐aryl‐9H‐pyrido [3, 4‐b] indol‐3‐yl) methylene] indolin‐2‐one
hybrids were synthesized and evaluated for their in vitro cytotoxic activity against a panel of …
hybrids were synthesized and evaluated for their in vitro cytotoxic activity against a panel of …
Post‐Pictet‐Spengler Cyclization (PPSC): A Strategy to Synthesize Polycyclic β‐Carboline‐Derived Natural Products and Biologically Active N‐Heterocycles
Pictet‐Spengler reaction is a typical condensation reaction of β‐arylethylamine or
Tryptamine with an aldehyde or ketone followed by ring closure to generate …
Tryptamine with an aldehyde or ketone followed by ring closure to generate …
Iodine-catalyzed chemoselective dehydrogenation and aromatization of tetrahydro-β-carbolines: A short synthesis of Kumujian-C, Eudistomin-U, Norharmane …
S Gaikwad, D Kamble, P Lokhande - Tetrahedron Letters, 2018 - Elsevier
Temperature controlled chemoselective dehydrogenation and aromatization of tetrahydro-β-
carbolines, using molecular I 2 and H 2 O 2, in DMSO solvent affords a practical access to a …
carbolines, using molecular I 2 and H 2 O 2, in DMSO solvent affords a practical access to a …