Estrogen is a fundamental regulator of the metabolic system of the female brain and body.
Within the brain, estrogen regulates glucose transport, aerobic glycolysis, and mitochondrial …

Adult neurogenesis, a complex process by which stem cells in the hippocampal brain region
differentiate and proliferate into new neurons and other resident brain cells, is known to be …

Major depressive disorder is a heritable psychiatric syndrome that appears to be associated
with subtle cellular and molecular alterations in a complex neural network. The affected …

The presence of neural stem cells (NSCs) and the production of new neurons in the adult
brain have received great attention from scientists and the public because of implications to …

Ghrelin is a peptide hormone produced and secreted in the stomach. Numerous studies
over the past decade demonstrate its importance in food intake, body-weight regulation and …

Augmenting hippocampal neurogenesis represents a potential new strategy for treating
depression. Here we test this possibility by comparing hippocampal neurogenesis in …

The birth, maturation, and integration of new neurons in the adult hippocampus regulates
specific learning and memory processes, responses to stress, and antidepressant treatment …

Ghrelin is a stomach hormone normally associated with feeding behavior and energy
homeostasis. Recent studies highlight that ghrelin targets the brain to regulate a diverse …

The beneficial effects of calorie restriction (CR) have been described at both organismal and
cellular levels in multiple organs. However, our understanding of the causal mediators of …

Abstract “Are new neurons added in the adult mammalian brain?”“Do neural stem cells
activate following CNS diseases?”“How can we modulate their activation to promote …