Design, printing, and engineering of regenerative biomaterials for personalized bone healthcare

Z Jia, X Xu, D Zhu, Y Zheng - Progress in Materials Science, 2023 - Elsevier
Trauma-and disease-related skeletal defects and illnesses are plaguing millions of people
especially in an ageing globe. Recently, the convergence of additive manufacturing (AM) …

[HTML][HTML] Silk fibroin-based biomaterials for cartilage/osteochondral repair

Z Zhou, J Cui, S Wu, Z Geng, J Su - Theranostics, 2022 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is a common joint disease with a high disability rate. In addition, OA not
only causes great physiological and psychological harm to patients, but also puts great …

Progress of microfluidic hydrogel‐based scaffolds and organ‐on‐chips for the cartilage tissue engineering

H Tolabi, N Davari, M Khajehmohammadi… - Advanced …, 2023 - Wiley Online Library
Cartilage degeneration is among the fundamental reasons behind disability and pain across
the globe. Numerous approaches have been employed to treat cartilage diseases …

Mechanics of bioinspired functionally graded soft-hard composites made by multi-material 3D printing

MJ Mirzaali, AH De La Nava, D Gunashekar… - Composite …, 2020 - Elsevier
Functional gradients are material transitions that are found in nature and are known to result
in materials with superior properties and multiple functionalities. The emerging multi …

Patterned, organoid-based cartilaginous implants exhibit zone specific functionality forming osteochondral-like tissues in vivo

GN Hall, WL Tam, KS Andrikopoulos, L Casas-Fraile… - Biomaterials, 2021 - Elsevier
Tissue engineered constructs have the potential to respond to the unmet medical need of
treating deep osteochondral defects. However, current tissue engineering strategies …

Joint-on-chip platforms: entering a new era of in vitro models for arthritis

CA Paggi, LM Teixeira, S Le Gac… - Nature Reviews …, 2022 - nature.com
Arthritis affects millions of people worldwide. With only a few disease-modifying drugs
available for treatment of rheumatoid arthritis and none for osteoarthritis, a clear need exists …

Osteochondral interface: regenerative engineering and challenges

N Yildirim, A Amanzhanova… - ACS Biomaterials …, 2023 - ACS Publications
Osteochondral (OC) defects are debilitating for patients and represent a significant clinical
problem for orthopedic surgeons as well as regenerative engineers due to their potential …

[HTML][HTML] Initiation and progression of dental-stimulated temporomandibular joints osteoarthritis

Q Liu, H Yang, M Zhang, J Zhang, L Lu, S Yu… - Osteoarthritis and …, 2021 - Elsevier
Temporomandibular joint (TMJ), a site that is often impacted by osteoarthritis (OA), is
biomechanically linked with dental occlusion. Tissue responses in TMJ condyle to …

Injectable hydrogels: a new paradigm for osteochondral tissue engineering

YP Singh, JC Moses, N Bhardwaj… - Journal of Materials …, 2018 - pubs.rsc.org
Osteochondral tissue engineering has become a promising strategy for repairing focal
chondral lesions and early osteoarthritis (OA), which account for progressive joint pain and …

A novel RGB-trichrome staining method for routine histological analysis of musculoskeletal tissues

F Gaytan, C Morales, C Reymundo… - Scientific reports, 2020 - nature.com
Morphometry and histology are essential approaches for investigation and diagnosis of
musculo-skeletal disorders. Despite the advent of revolutionary methods of image analysis …