Non-alcoholic fatty liver disease (NAFLD) and its inflammatory form, non-alcoholic
steatohepatitis (NASH), have quickly risen to become the most prevalent chronic liver …

Complications of allogeneic hematopoietic stem cell transplantation (HSCT) remain barriers
to its wider application for a variety of diseases. Graft-versus-host disease (GVHD) is the …

Transforming growth factor-β1 (TGF-β1) is a multifunctional growth factor that has profound
regulatory effects on many developmental and physiological processes. Disruption of the …

Bacterial lipopolysaccharide (LPS) provokes a vigorous, generalized proinflammatory state
in the infected host. Genetic regulation of this response has been localized to the Lps locus …

Escherichia coli lipopolysaccharide (LPS)-induced nitrate biosynthesis was studied in LPS-
sensitive C3H/He and LPS-resistant C3H/HeJ mice. Intraperitoneal injection of 15 …

Donor T cell responses to host alloantigen are known predictors for graft-versus-host
disease (GVHD); however, the effect of donor responsiveness to an inflammatory stimulus …

Publisher Summary This chapter discusses the nature of endotoxins and their interactions
with cells of the immune system. The direct interaction of endotoxin with B lymphocytes …

A disease closely resembling human alopecia areata was found in a large production
colony of C3H/HeJ mice that had no evidence of thyroid dysfunction or an infectious …

Abstract Background/Aims: C3H/HeJ mice at the Jackson Laboratory have periodically been
culled because of the occurrence of soft feces, perianal ulceration, and rightsided colitis. No …

Mice that are unresponsive to lipopolysaccharide (LPS)(strain C3H/HeJ) can be rendered
LPS-sensitive by the adoptive transfer of bone marrow cells from LPSsensitive mice (strain …