Revisiting host-pathogen interactions in cystic fibrosis lungs in the era of CFTR modulators

CMP Ribeiro, MG Higgs, MS Muhlebach… - International Journal of …, 2023 - mdpi.com
Cystic fibrosis transmembrane conductance regulator (CFTR) modulators, a new series of
therapeutics that correct and potentiate some classes of mutations of the CFTR, have …

Potential opportunities and challenges for infection prevention and control for cystic fibrosis in the modern era

L Murray, L Saiman - Current Opinion in Infectious Diseases, 2022 - journals.lww.com
Potential opportunities and challenges for infection prevent... : Current Opinion in Infectious
Diseases Potential opportunities and challenges for infection prevention and control for cystic …

Competitive fitness of Pseudomonas aeruginosa isolates in human and murine precision-cut lung slices

N Cramer, ML Nawrot, L Wege, M Dorda… - Frontiers in Cellular …, 2022 - frontiersin.org
Chronic respiratory infections with the gram-negative bacterium Pseudomonas aeruginosa
are an important co-morbidity for the quality of life and prognosis of people with cystic …

[HTML][HTML] Use of elexacaftor/tezacaftor/ivacaftor leads to changes in detection frequencies of Staphylococcus aureus and Pseudomonas aeruginosa dependent on age …

AM Dittrich, S Sieber, L Naehrlich, M Burkhart… - International Journal of …, 2024 - Elsevier
Objectives The impressive improvements of cystic fibrosis (CF) transmembrane conductance
regulator (CFTR) function by elexacaftor/tezacaftor/ivacaftor (ETI) result in changes in the …

Antibiotic tolerance and treatment outcomes in cystic fibrosis methicillin-resistant Staphylococcus aureus Infections

KY Lu, NJ Wagner, AZ Velez, A Ceppe… - Microbiology …, 2023 - Am Soc Microbiol
Methicillin-resistant Staphylococcus aureus (MRSA) is highly prevalent in US cystic fibrosis
(CF) patients and is associated with worse clinical outcomes in CF. These infections often …

Seasonal and climatic influence on respiratory infections in children with cystic fibrosis

J Mésinèle, M Ruffin, L Guillot, PY Boëlle, H Corvol - Scientific Reports, 2024 - nature.com
Abstract Pseudomonas aeruginosa (Pa) and Methicillin susceptible Staphylococcus aureus
(MSSA) are the predominant bacteria found in the airways of people with cystic fibrosis …

Association of Pseudomonas aeruginosa incident infections with adherence to cystic fibrosis foundation care guidelines

KS Shah, L Saiman, JJ LiPuma, MR Kosorok… - Journal of Cystic …, 2024 - Elsevier
Background Care guidelines for cystic fibrosis (CF) have been developed to enhance
consistent care and to improve health outcomes. We determined if adherence to CF care …

Infection control in cystic fibrosis: evolving perspectives and challenges

AM Jones - Current Opinion in Pulmonary Medicine, 2022 - journals.lww.com
Infection control in cystic fibrosis: evolving perspectives... : Current Opinion in Pulmonary
Medicine Infection control in cystic fibrosis: evolving perspectives and challenges : Current …

Predicting risk-adjusted incidence rates of methicillin-resistant Staphylococcus Aureus and Pseudomonas Aeruginosa in cystic fibrosis programs in the United States

W Stoudemire, X Jiang, JJ Zhou, MR Kosorok… - Journal of Cystic …, 2022 - Elsevier
Background Healthcare-associated transmission of methicillin-resistant Staphylococcus
aureus (MRSA) and Pseudomonas aeruginosa occurs for people with cystic fibrosis (CF) …

Pathogen detection. The bread and butter

JT Forton - Journal of Cystic Fibrosis, 2022 - cysticfibrosisjournal.com
Modulator therapies for people with cystic fibrosis (CF) have been transformative. But not so,
apparently, on the composition of airway microbiology [1]. Pseudomonas aeruginosa (Psa) …