Diabetic kidney disease (DKD) is the main cause of end-stage renal disease worldwide, and
there is a lack of effective treatment strategies. Autophagy is a highly conserved lysosomal …

The imbalance between proliferation and death of kidney resident cells is a crucial factor in
the development of acute or chronic renal dysfunction. Acute kidney injury (AKI) is often …

Early pathogenesis of ischemia-reperfusion (I/R)-induced acute kidney injury (AKI) is
dominated by intracellular calcium overload, which induces oxidative stress, intracellular …

As the quality of life improves, the incidence of diabetes mellitus and its microvascular
complications (DMC) continues to increase, posing a threat to people's health and …

Background Acute kidney injury (AKI) due to ischemia-reperfusion (IR) is a serious and
frequent complication in clinical settings, and mortality rates remain high. There are well …

Acute kidney injury (AKI) constitutes a prevalent clinical syndrome characterized by elevated
morbidity and mortality rates, emerging as a significant public health issue. This study …

Acute kidney injury (AKI) has emerged as a global health crisis, surpassing mortality rates
associated with several cancers and heart failure. The lack of effective therapies, coupled …

Objective Deoxynivalenol (DON) is a common fungal toxin that poses significant health risks
to humans and animals. The present study aimed to investigate the adverse effects and …

The endoplasmic reticulum (ER) is an important organelle in eukaryotic cells, responsible for
a range of biological functions such as the secretion, modification and folding of proteins …

Objectives This study examined the role of endoplasmic reticulum stress in pediatric acute
kidney injury and the therapeutic effect of midbrain astrocyte-derived neurotrophic factor …