Hierarchical nanomaterials assembled from peptoids and other sequence-defined synthetic polymers

Z Li, B Cai, W Yang, CL Chen - Chemical Reviews, 2021 - ACS Publications
In nature, the self-assembly of sequence-specific biopolymers into hierarchical structures
plays an essential role in the construction of functional biomaterials. To develop synthetic …

Engineering precise sequence-defined polymers for advanced functions

Q Shi, Z Deng, M Hou, X Hu, S Liu - Progress in Polymer Science, 2023 - Elsevier
Unlike natural macromolecules (eg, nucleic acids and proteins) possessing precisely
defined molar mass, chain sequence, chirality, and topology, synthetic polymers are typically …

Bioinspired Catalyst Design Principles: Progress in Emulating Properties of Enzymes in Synthetic Catalysts

B Ginovska, OY Gutiérrez, A Karkamkar, MS Lee… - ACS …, 2023 - ACS Publications
Catalysis enables many aspects of modern life, including fuels, products, plastics, and
medicines. Recent advances in catalysis have enabled us to realize higher efficiencies and …

Emerging trends in solution self-assembly of block copolymers

Z Deng, S Liu - Polymer, 2020 - Elsevier
Since the foundation of macromolecular science by Staudinger, advances in polymer
chemistry have unveiled enormous avenues for controlling chemical structures at the …

Precision Sequence‐Defined Polymers: From Sequencing to Biological Functions

Q Shi, Z Zhang, S Liu - Angewandte Chemie International …, 2024 - Wiley Online Library
Precise sequence‐defined polymers (SDPs) with uniform chain‐to‐chain structure including
chain length, unit sequence, and end functionalities represent the pinnacle of sophistication …

Submonomer synthesis of sequence defined peptoids with diverse side-chains

MD Connolly, S Xuan, N Molchanova… - Methods in …, 2021 - Elsevier
Peptoids are a diverse family of sequence-defined oligomers of N-substituted glycine
monomers, that can be readily accessed by the solid-phase submonomer synthesis method …

Thermodynamic Basis for the Stabilization of Helical Peptoids by Chiral Sidechains

S Alamdari, K Torkelson, X Wang… - The Journal of …, 2023 - ACS Publications
Peptoids are a class of highly customizable biomimetic foldamers that retain properties from
both proteins and polymers. It has been shown that peptoids can adopt peptide-like …

Assembly of short amphiphilic peptoids into nanohelices with controllable supramolecular chirality

R Zheng, M Zhao, JS Du, TR Sudarshan… - Nature …, 2024 - nature.com
A long-standing challenge in bioinspired materials is to design and synthesize synthetic
materials that mimic the sophisticated structures and functions of natural biomaterials, such …

Synthesis and properties of polypeptoid‐containing block copolymers: A review

P Zhou, T Shen, J Ling - Journal of Polymer Science, 2021 - Wiley Online Library
Polypeptoids, with similar structure to polypeptides, are nowadays rising stars due to their
excellent solubility, processibility, enzymatic stability, and biocompatibility. Attractive …

Quantifying Polypeptoid Conformational Landscapes through Integrated Experiment and Simulation

S Jiao, A DeStefano, JI Monroe, M Barry… - …, 2021 - ACS Publications
We combine experiment and simulation to develop a powerful, validated approach for
characterizing the conformational landscapes of disordered polypeptoids. Polypeptoids …