Catalytic enantioselective ring-opening reactions of cyclopropanes

V Pirenne, B Muriel, J Waser - Chemical Reviews, 2020 - ACS Publications
This review describes the development of enantioselective methods for the ring opening of
cyclopropanes. Both approaches based on the reaction of nonchiral cyclopropanes and …

Transition metal-catalyzed selective carbon–carbon bond cleavage of vinylcyclopropanes in cycloaddition reactions

J Wang, SA Blaszczyk, X Li, W Tang - Chemical reviews, 2020 - ACS Publications
In this review, transition metal-catalyzed methodologies and applications that exploit C–C
bond cleavage of vinylcyclopropanes (VCPs) are summarized with a focus on cycloaddition …

Recent advances in the synthesis of cyclopropanes

W Wu, Z Lin, H Jiang - Organic & biomolecular chemistry, 2018 - pubs.rsc.org
Cyclopropanes, one of the most important strained rings, have gained much attention for
more than a century because of their interesting and unique reactivity. They not only exist in …

Recent advances in ring-opening of donor acceptor cyclopropanes using C-nucleophiles

K Ghosh, S Das - Organic & Biomolecular Chemistry, 2021 - pubs.rsc.org
Ring-opening transformations of donor–acceptor cyclopropanes (DAC) with carbon-
centered nucleophiles is a simple, straight-forward approach to 1, 3-bifunctional compounds …

Catalytic Asymmetric Cyclopropanations with Nonstabilized Carbenes

KE Berger, RJ Martinez, J Zhou… - Journal of the American …, 2023 - ACS Publications
Cyclopropanes are common building blocks in pharmaceuticals, agrochemicals, and
organic materials. The most general methods for the synthesis of chiral cyclopropanes are …

Visible-light-induced dearomatization of indoles/pyrroles with vinylcyclopropanes: expedient synthesis of structurally diverse polycyclic indolines/pyrrolines

M Zhu, XL Huang, S Sun, C Zheng… - Journal of the American …, 2021 - ACS Publications
Visible-light-induced cycloaddition reactions initiated via energy-transfer processes have
recently evolved as powerful methods for the construction of strained cyclic molecules that …

Donor–Acceptor Cyclopropanes as an Expedient Building Block Towards the Construction of Nitrogen‐Containing Molecules: An Update

P Singh, RK Varshnaya, R Dey… - Advanced Synthesis & …, 2020 - Wiley Online Library
Nitrogen‐containing molecules are the key structural constituent of many pharmaceutical
compounds that play a pivotal role in drug development. Owing to their multifaceted …

Selective carbon–carbon bond cleavage of cyclopropylamine derivatives

OO Sokolova, JF Bower - Chemical Reviews, 2020 - ACS Publications
This review summarizes synthetic developments reported from 1987 to 2019 that exploit C–
C single bond cleavage of cyclopropylamine-based systems. The synthetic and mechanistic …

Recent Developments in Transition Metal‐Catalyzed Dearomative Cyclizations of Indoles as Dipolarophiles for the Construction of Indolines

G Huang, B Yin - Advanced Synthesis & Catalysis, 2019 - Wiley Online Library
Fused polycyclic indoline skeletons are found in many natural products and bioactive
molecules. Several approaches, including dearomative cyclization of functionalized indoles …

Palladium‐Catalyzed Asymmetric [4+ 2] Cycloaddition of 2‐Methylidenetrimethylene Carbonate with Alkenes: Access to Chiral Tetrahydropyran‐Fused Spirocyclic …

B Mao, H Liu, Z Yan, Y Xu, J Xu… - Angewandte Chemie …, 2020 - Wiley Online Library
Abstract A palladium‐catalyzed asymmetric [4+ 2] cycloaddition of 2‐
methylidenetrimethylene carbonate with alkenes derived from pyrazolones, indandione, or …