High-throughput glycomic methods

I Trbojević-Akmačić… - Chemical …, 2022 - ACS Publications
Glycomics aims to identify the structure and function of the glycome, the complete set of
oligosaccharides (glycans), produced in a given cell or organism, as well as to identify …

Multimarkers of metabolic malnutrition and inflammation and their association with mortality risk in cardiac catheterisation patients: a prospective, longitudinal …

JD Otvos, I Shalaurova, HT May… - The Lancet Healthy …, 2023 - thelancet.com
Background Complex and incompletely understood metabolic dysfunction associated with
inflammation and protein–energy wasting contribute to the increased mortality risk of older …

The glycobiology of pulmonary arterial hypertension

S Vang, P Cochran, J Sebastian Domingo, S Krick… - Metabolites, 2022 - mdpi.com
Pulmonary arterial hypertension (PAH) is a progressive pulmonary vascular disease of
complex etiology. Cases of PAH that do not receive therapy after diagnosis have a low …

False-positive glycopeptide identification via in-FAIMS fragmentation

V Rangel-Angarita, KE Mahoney, C Kwon, R Sarker… - JACS Au, 2023 - ACS Publications
High-field asymmetric waveform ion mobility spectrometry (FAIMS) separates glycopeptides
in the gas phase prior to mass spectrometry (MS) analysis, thus offering the potential to …

The N-Glycosylation of Total Plasma Proteins and IgG in Atrial Fibrillation

B Plavša, J Szavits-Nossan, A Blivajs, B Rapčan… - Biomolecules, 2023 - mdpi.com
Atrial fibrillation is a disease with a complex pathophysiology, whose occurrence and
persistence are caused not only by aberrant electrical signaling in the heart, but by the …

Clinical glycoproteomics: methods and diseases

Y Wang, K Lei, L Zhao, Y Zhang - MedComm, 2024 - Wiley Online Library
Glycoproteins, representing a significant proportion of posttranslational products, play
pivotal roles in various biological processes, such as signal transduction and immune …

High-throughput N-glycan analysis in aging and inflammaging: State of the art and future directions

A Cindrić, T Pribić, G Lauc - Seminars in Immunology, 2024 - Elsevier
As the global population ages at an unprecedented rate, the prevalence of age-related
diseases is increasing, making inflammaging–a phenomenon characterized by a chronic …

[HTML][HTML] Immunoglobulin G glycosylation and its alterations in aging-related diseases: IgG glycosylation with aging-related diseases

Y Wu, Z Zhang, L Chen, S Sun - Acta Biochimica et Biophysica …, 2024 - pmc.ncbi.nlm.nih.gov
Immunoglobulin G (IgG) is an important serum glycoprotein and a major component of
antibodies. Glycans on IgG affect the binding of IgG to the Fc receptor or complement C1q …

The effects of glycosylation modifications on monocyte recruitment and foam cell formation in atherosclerosis

D Teng, W Wang, W Jia, J Song, L Gong… - … et Biophysica Acta (BBA …, 2024 - Elsevier
The monocyte recruitment and foam cell formation have been intensively investigated in
atherosclerosis. Nevertheless, as the study progressed, it was obvious that crucial …

Changes in serum IgG glycosylation patterns for abdominal aortic aneurysm patients

S Li, J Meng, Y Lv, Q Wang, X Tian, M Li… - Journal of …, 2022 - mdpi.com
Background: B cells and autoantibodies play an important role in the pathogenesis of
abdominal aortic aneurysm (AAA). IgG glycosylations are highly valued as potential disease …