Mechanisms of cisplatin-induced acute kidney injury: pathological mechanisms, pharmacological interventions, and genetic mitigations
KR McSweeney, LK Gadanec, T Qaradakhi, BA Ali… - Cancers, 2021 - mdpi.com
Simple Summary Nephrotoxicity is the dose-limiting factor of cisplatin treatment.
Nephrotoxicity is characterized by reduced kidney function. Although an often-reversible …
Nephrotoxicity is characterized by reduced kidney function. Although an often-reversible …
[HTML][HTML] What's sex got to do with COVID-19? Gender-based differences in the host immune response to coronaviruses
N Gadi, SC Wu, AP Spihlman, VR Moulton - Frontiers in immunology, 2020 - frontiersin.org
The novel severe acute respiratory syndrome coronavirus 2, the cause of the coronavirus
disease 2019 (COVID-19) pandemic, has ravaged the world, with over 22 million total cases …
disease 2019 (COVID-19) pandemic, has ravaged the world, with over 22 million total cases …
Single-cell profiling of CNS border compartment leukocytes reveals that B cells and their progenitors reside in non-diseased meninges
The CNS is ensheathed by the meninges and cerebrospinal fluid, and recent findings
suggest that these CNS-associated border tissues have complex immunological functions …
suggest that these CNS-associated border tissues have complex immunological functions …
Central regulation of stress-evoked peripheral immune responses
Stress-linked psychiatric disorders, including anxiety and major depressive disorder, are
associated with systemic inflammation. Recent studies have reported stress-induced …
associated with systemic inflammation. Recent studies have reported stress-induced …
Neutrophils induce paracrine telomere dysfunction and senescence in ROS‐dependent manner
Cellular senescence is characterized by an irreversible cell cycle arrest as well as a pro‐
inflammatory phenotype, thought to contribute to aging and age‐related diseases …
inflammatory phenotype, thought to contribute to aging and age‐related diseases …
Eosinophils from A to Z
L Gigon, T Fettrelet, S Yousefi, D Simon, HU Simon - Allergy, 2023 - Wiley Online Library
Eosinophils are bone marrow‐derived granulocytes and are found in low numbers in the
peripheral blood of healthy subjects. In type 2 inflammatory diseases, eosinopoiesis in the …
peripheral blood of healthy subjects. In type 2 inflammatory diseases, eosinopoiesis in the …
SARS-CoV-2 induced intestinal responses with a biomimetic human gut-on-chip
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic. Clinical evidence …
syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic. Clinical evidence …
Lactobacillus fermentum species ameliorate dextran sulfate sodium-induced colitis by regulating the immune response and altering gut microbiota
YJ Jang, WK Kim, DH Han, K Lee, G Ko - Gut microbes, 2019 - Taylor & Francis
We evaluated immunometabolic functions of novel Lactobacillus fermentum strains (KBL374
and KBL375) isolated from feces of healthy Koreans. The levels of inflammatory cytokines …
and KBL375) isolated from feces of healthy Koreans. The levels of inflammatory cytokines …
How do chemokines navigate neutrophils to the target site: Dissecting the structural mechanisms and signaling pathways
K Rajarathnam, M Schnoor, RM Richardson… - Cellular signalling, 2019 - Elsevier
Chemokines play crucial roles in combating microbial infection and initiating tissue repair by
recruiting neutrophils in a timely and coordinated manner. In humans, no less than seven …
recruiting neutrophils in a timely and coordinated manner. In humans, no less than seven …
CXCL1: Gene, Promoter, Regulation of Expression, mRNA Stability, Regulation of Activity in the Intercellular Space
J Korbecki, K Barczak, I Gutowska, D Chlubek… - International journal of …, 2022 - mdpi.com
CXCL1 is one of the most important chemokines, part of a group of chemotactic cytokines
involved in the development of many inflammatory diseases. It activates CXCR2 and, at high …
involved in the development of many inflammatory diseases. It activates CXCR2 and, at high …