Myelin is critical for healthy brain function. An accurate in vivo measure of myelin content
has important implications for understanding brain plasticity and neurodegenerative …

Myelin water imaging (MWI) is an MRI imaging biomarker for myelin. This method can
generate an in vivo whole‐brain myelin water fraction map in approximately 10 minutes. It …

Rapid and efficient transmission of electric signals among neurons of vertebrates is ensured
by myelin‐insulating sheaths surrounding axons. Human cognition, sensation, and motor …

MRI relaxometry is sensitive to a variety of tissue characteristics in a complex manner, which
makes it both attractive and challenging for characterizing tissue. This article reviews the …

White matter (WM) microstructural properties change across the adult lifespan and with
neuronal diseases. Understanding microstructural changes due to aging is paramount to …

Tremendous efforts have been made in the last decade to advance cutting-edge MRI
technology in pursuit of mapping structural connectivity in the living human brain with …

Purpose To create a realistic in silico head phantom for the second QSM reconstruction
challenge and for future evaluations of processing algorithms for QSM. Methods We created …

Damage to myelin is a key feature of multiple sclerosis (MS) pathology. Magnetic resonance
imaging (MRI) has revolutionized our ability to detect and monitor MS pathology in vivo …

Abstract Background and Purpose The objective is to demonstrate feasibility of separating
magnetic sources in quantitative susceptibility mapping (QSM) by incorporating magnitude …

Background The g-ratio, quantifying the comparative thickness of the myelin sheath
encasing an axon, is a geometrical invariant that has high functional relevance because of …