Blood groups in infection and host susceptibility

L Cooling - Clinical microbiology reviews, 2015 - Am Soc Microbiol
Blood group antigens represent polymorphic traits inherited among individuals and
populations. At present, there are 34 recognized human blood groups and hundreds of …

Aquaporins: important but elusive drug targets

AS Verkman, MO Anderson… - Nature reviews Drug …, 2014 - nature.com
The aquaporins (AQPs) are a family of small, integral membrane proteins that facilitate water
transport across the plasma membranes of cells in response to osmotic gradients. Data from …

[HTML][HTML] In vitro anti-inflammatory and skin protective properties of Virgin coconut oil

SR Varma, TO Sivaprakasam, I Arumugam… - Journal of traditional and …, 2019 - Elsevier
Virgin coconut oil (VCO) has been traditionally used as moisturizer since centuries by
people in the tropical region. Clinical studies have revealed that VCO improves the …

The phagocyte NOX2 NADPH oxidase in microbial killing and cell signaling

WM Nauseef - Current opinion in immunology, 2019 - Elsevier
Highlights•Phagocyte NOX2 NADPH oxidase generates oxidants.•Optimal antimicrobial
action in phagosomes depends on oxidants.•Precise mechanisms of oxidant-dependent …

Inhibitors of mammalian aquaporin water channels

M Abir-Awan, P Kitchen, MM Salman… - International journal of …, 2019 - mdpi.com
Aquaporins (AQPs) are water channel proteins that are essential to life, being expressed in
all kingdoms. In humans, there are 13 AQPs, at least one of which is found in every organ …

[HTML][HTML] Immunogenetics associated with severe coccidioidomycosis

AP Hsu, A Korzeniowska, CC Aguilar, J Gu, E Karlins… - JCI insight, 2022 - ncbi.nlm.nih.gov
Disseminated coccidioidomycosis (DCM) is caused by Coccidioides, pathogenic fungi
endemic to the southwestern United States and Mexico. Illness occurs in approximately 30 …

New perspectives on the potential role of aquaporins (AQPs) in the physiology of inflammation

R Meli, C Pirozzi, A Pelagalli - Frontiers in physiology, 2018 - frontiersin.org
Aquaporins (AQPs) are emerging, in the last few decades, as critical proteins regulating
water fluid homeostasis in cells involved in inflammation. AQPs represent a family of …

Evidence for bidirectional endocannabinoid transport across cell membranes

A Chicca, J Marazzi, S Nicolussi, J Gertsch - Journal of Biological Chemistry, 2012 - ASBMB
Despite extensive research on the trafficking of anandamide (AEA) across cell membranes,
little is known about the membrane transport of other endocannabinoids, such as 2 …

lncRNA RMRP Prevents Mitochondrial Dysfunction and Cardiomyocyte Apoptosis via the miR-1-5p/hsp70 Axis in LPS-Induced Sepsis Mice

Y Han, Y Cai, X Lai, Z Wang, S Wei, K Tan, M Xu, H Xie - Inflammation, 2020 - Springer
Both long non-coding RNA (lncRNA) RMRP and heat shock protein (HSP) 70 have been
known to play crucial roles in inflammation. The present study investigated the roles of …

[HTML][HTML] Peroxiporins and Oxidative Stress: Promising Targets to Tackle Inflammation and Cancer

IV da Silva, M Mlinarić, AR Lourenço… - International journal of …, 2024 - mdpi.com
Peroxiporins are a specialized subset of aquaporins, which are integral membrane proteins
primarily known for facilitating water transport across cell membranes. In addition to the …