Accuracy of diagnosis among clinical malaria patients: comparing microscopy, RDT and a highly sensitive quantitative PCR looking at the implications for …

S Opoku Afriyie, TK Addison, Y Gebre, AH Mutala… - Malaria Journal, 2023 - Springer
Abstract Background The World Health Organization recommends parasitological
confirmation of all suspected malaria cases by microscopy or rapid diagnostic tests (RDTs) …

[HTML][HTML] Polymerase chain reaction-based malaria diagnosis can be increasingly adopted during current phase of malaria elimination in India

M Rahi, R Sharma, P Saroha… - The American Journal …, 2022 - ncbi.nlm.nih.gov
Despite commendable progress in control of malaria in India and other countries, there are
hidden reservoirs of parasites in human hosts that continually feed malaria transmission …

Molecular detection of sub-microscopic infections and Plasmodium falciparum histidine-rich protein-2 and 3 gene deletions in pre-elimination settings of South Africa

OO Oyegoke, OP Akoniyon, L Maharaj, TS Adewumi… - Scientific Reports, 2024 - nature.com
South Africa's efforts toward eliminating malaria have positioned the country in the pre-
elimination stage. Imported and sub-microscopic cases still contribute to the persistence of …

Hyper-prevalence of submicroscopic Plasmodium falciparum infections in a rural area of western Kenya with declining malaria cases

KO Ochwedo, CJ Omondi, EO Magomere, JO Olumeh… - Malaria journal, 2021 - Springer
Background The gold standard for diagnosing Plasmodium falciparum infection is
microscopic examination of Giemsa-stained peripheral blood smears. The effectiveness of …

[HTML][HTML] Understanding the intransigence of malaria in Malawi

LM Cohee, J Goupeyou-Youmsi… - The American journal …, 2022 - ncbi.nlm.nih.gov
Despite the scale-up of interventions against malaria over the past decade, this disease
remains a leading threat to health in Malawi. To evaluate the epidemiology of both …

Statistical haemoglobin thresholds to define anaemia across the lifecycle

S Braat, K Fielding, J Han, VE Jackson, S Zaloumis… - medRxiv, 2023 - medrxiv.org
Detection of anaemia is critical for clinical medicine and public health. Current WHO values
that define anaemia are statistical thresholds (5th centile) set over 50 years ago, and are …

Prevalence of subpatent Plasmodium falciparum infections in regions with varying transmission intensities and implications for malaria elimination in Mainland …

MD Seth, ZR Popkin-Hall, RA Madebe, R Budodo… - medRxiv, 2024 - medrxiv.org
Background: Subpatent Plasmodium falciparum infections, defined as infections with
parasitaemia density below the detection limit of routine malaria diagnostic tests, contribute …

Humoral Immune Responses to P. falciparum Circumsporozoite Protein (Pfcsp) Induced by the RTS, S Vaccine – Current Update

P Ngulube - Infection and Drug Resistance, 2023 - Taylor & Francis
Malaria vaccines targeting the circumsporozoite protein (CSP) of the P. falciparum parasite
have been overall relatively promising. RTS, S is a pre-erythrocytic recombinant protein …

Infection submicroscopique à Plasmodium falciparum en zone d'endémie palustre

JC Biteghe-Bi-Essone - Ann. Afr. Med, 2022 - ajol.info
La détection des parasites responsables du paludisme se fait par microscopie ou par des
tests de diagnostic rapide mais ces techniques ne permettent pas de détecter tous les cas …

Functional Analysis of Immune Response to Plasmodium Falciparum Gametocytes Surface Antigens Pfs25, Pfs48/45 and Pfs230

KO Ochwedo - 2022 - erepository.uonbi.ac.ke
Malaria Transmission Blocking Vaccine (MTBV) candidates capable of eliciting effective and
long-lasting protection, thereby blocking or reducing community Plasmodium falciparum …