[HTML][HTML] Polyethylene glycol 35 as a perfusate additive for mitochondrial and glycocalyx protection in HOPE liver preservation

A Panisello Rosello, R Teixeira da Silva… - International Journal of …, 2020 - mdpi.com
Organ transplantation is a multifactorial process in which proper graft preservation is a
mandatory step for the success of the transplantation. Hypothermic preservation of …

[HTML][HTML] Polyethylene glycols: An effective strategy for limiting liver ischemia reperfusion injury

G Pasut, A Panisello, E Folch-Puy, A Lopez… - World journal of …, 2016 - ncbi.nlm.nih.gov
Liver ischemia-reperfusion injury (IRI) is an inherent feature of liver surgery and liver
transplantation in which damage to a hypoxic organ (ischemia) is exacerbated following the …

AMPK involvement in endoplasmic reticulum stress and autophagy modulation after fatty liver graft preservation: a role for melatonin and trimetazidine cocktail

MA Zaouali, E Boncompagni, RJ Reiter… - Journal of pineal …, 2013 - Wiley Online Library
Ischemia/reperfusion injury (IRI) associated with liver transplantation plays an important role
in the induction of graft injury. Prolonged cold storage remains a risk factor for liver graft …

Anti-inflammatory and hepatoprotective effects of Ganoderma lucidum polysaccharides against carbon tetrachloride-induced liver injury in Kunming mice

YS Chen, QZ Chen, ZJ Wang, C Hua - Pharmacology, 2019 - karger.com
Background: Ganoderma lucidum Polysaccharides (GLPS) were found to possess various
pharmacological properties including anti-inflammatory and hepatoprotective activities …

[HTML][HTML] Protective effect of Salvia miltiorrhiza polysaccharides on liver injury in chickens

C Han, Y Wei, X Wang, C Ba, W Shi - Poultry Science, 2019 - Elsevier
This study investigated the effects of Salvia miltiorrhiza polysaccharides (SMPs) on the injury
of chicken hepatocytes in vitro and in vivo. In in vitro studies primary cultured hepatocytes …

[HTML][HTML] Defining the optimal duration for normothermic regional perfusion in the kidney donor: A porcine preclinical study

T Kerforne, G Allain, S Giraud, D Bon… - American Journal of …, 2019 - Elsevier
Kidneys from donation after circulatory death (DCD) are highly sensitive to ischemia-
reperfusion injury and thus require careful reconditioning, such as normothermic regional …

[HTML][HTML] A potential route to reduce ischemia/reperfusion injury in organ preservation

M Micó-Carnero, MA Zaouali, C Rojano-Alfonso… - Cells, 2022 - mdpi.com
The pathophysiological process of ischemia and reperfusion injury (IRI), an inevitable step
in organ transplantation, causes important biochemical and structural changes that can …

[HTML][HTML] Role of PEG35, mitochondrial ALDH2, and glutathione in cold fatty liver graft preservation: an IGL-2 approach

RG Bardallo, RT Da Silva, T Carbonell… - International Journal of …, 2021 - mdpi.com
The total damage inflicted on the liver before transplantation is associated with several
surgical manipulations, such as organ recovery, washout of the graft, cold conservation in …

Carvacrol suppresses the expression of inflammatory marker genes in D-galactosamine-hepatotoxic rats

B Aristatile, AH Al-Assaf, KV Pugalendi - Asian Pacific journal of tropical …, 2013 - Elsevier
OBJECTIVE: To unravel the mechanism of anti-inflammatory activity of carvacrol in D-
galactosamine (D-GalN)-induced hepatotoxic rats. METHODS: The mRNA and protein …

Protective effect of a polysaccharide from Rhizoma Atractylodis Macrocephalae on acute liver injury in mice

B Han, Y Gao, Y Wang, L Wang, Z Shang… - International Journal of …, 2016 - Elsevier
A homogeneous polysaccharide was isolated and purified from Rhizoma Atractylodis
Macrocephalae (RAM) and named PRAM2. Its average molecular weight was 19.6× 10 3 Da …