Thiophene‐containing compounds with antimicrobial activity

G Roman - Archiv der Pharmazie, 2022 - Wiley Online Library
Thiophene, as a member of the group of five‐membered heterocycles containing one
heteroatom, is one of the simplest heterocyclic systems. Many synthetic strategies allow the …

Nascent pharmacological advancement in adamantane derivatives

A Ragshaniya, V Kumar, RK Tittal… - Archiv der Pharmazie, 2024 - Wiley Online Library
The adamantane moiety has attracted significant attention since its discovery in 1933 due to
its remarkable structural, chemical, and medicinal properties. This molecule has a notable …

Spectroscopic, solvation effects and MD simulation of an adamantane-carbohydrazide derivative, a potential antiviral agent

LH Al-Wahaibi, M Abdalla, YS Mary… - Polycyclic Aromatic …, 2023 - Taylor & Francis
The spectroscopic, solvent effects, reactivity and MD simulations of N'-[(1E)-(2, 6-
dichlorophenyl-methylidene] adamantane-1-carbohydrazide (DMC) are reported. Solvation …

Novel Adamantane-Linked Isothiourea Derivatives as Potential Chemotherapeutic Agents: Synthesis, Structural Insights, and Antimicrobial/Anti-Proliferative Profiles

FAM Al-Omary, N Alvarez, LS Al-Rasheed, N Veiga… - ACS …, 2023 - ACS Publications
In this study, two adamantane-linked isothiourea derivatives containing a common 4-
chlorophenyl substituent coupled with 4-nitrobenzyl or 4-bromobenzyl moieties were …

Synthesis, structural and in vitro biological evaluation of diamondoid-decorated lipophilic organotin (IV) derivatives

TSB Baul, R Manne, A Duthie, LY Liew, J Chew… - Journal of …, 2021 - Elsevier
A series of diamondoid-decorated organotin (IV) derivatives of composition Me 3 Sn (L 1)(1),
Ph 3 Sn (L 1)(2),{[Me 2 Sn (L 1)] 2 O} 2 (3),[BzSn (O)(L 1)] 6 (4), Me 3 Sn (L 2) OH 2 (5),[Ph 3 …

Structural insights and docking analysis of adamantane-linked 1, 2, 4-triazole derivatives as potential 11β-HSD1 inhibitors

DA Osman, MA Macías, LH Al-Wahaibi, NH Al-Shaalan… - Molecules, 2021 - mdpi.com
The solid-state structural analysis and docking studies of three adamantane-linked 1, 2, 4-
triazole derivatives are presented. Crystal structure analyses revealed that compound 2 …

Weak Noncovalent Interactions in Three Closely Related Adamantane-Linked 1, 2, 4-Triazole N-Mannich Bases: Insights from Energy Frameworks, Hirshfeld Surface …

LH Al-Wahaibi, MA Macías, O Blacque, LS Zondagh… - Molecules, 2022 - mdpi.com
Structural analysis and docking studies of three adamantane-linked 1, 2, 4-triazole N-
Mannich bases (1–3) are presented. Compounds 1, 2 and 3 crystallized in the monoclinic P …

Efficient synthetic access to novel indolo [2, 3-b] quinoxaline-based heterocycles

AAO Abeed, T El-Emary, S Alharthi - Current Organic Synthesis, 2022 - ingentaconnect.com
Background: This paper showed the synthetic capability of the indolo [2, 3-b] quinoxaline
nucleus to be provided as an excellent precursor for the synthesis of various heterocyclic …