This systematic review and meta-analysis synthesised the post-1990 literature examining
the effect of human milk on morbidity, specifically necrotising enterocolitis (NEC), late onset …

Background In preterm newborns, the ductus arteriosus frequently fails to close and the
infants require medical or surgical closure of the patent ductus arteriosus (PDA). A PDA can …

Background Whilst the pharmacological profiles and mechanisms of antidepressants are
varied, there are common reasons why they might help people to stop smoking tobacco …

Background Non‐invasive positive pressure ventilation (NPPV) has been used to treat
respiratory distress due to acute cardiogenic pulmonary oedema (ACPE). We performed a …

Background This is the second update of a Cochrane Review (Issue 4, 2006). Pain and
distress from needle‐related procedures are common during childhood and can be reduced …

Background Stroke is the third leading cause of death and the most common cause of long‐
term disability. Severe narrowing (stenosis) of the carotid artery is an important cause of …

Background Infant formulas containing hydrolysed proteins have been widely advocated for
preventing allergic disease in infants, in place of standard cow's milk formula (CMF) …

Background Indomethacin is used as standard therapy to close a patent ductus arteriosus
(PDA) but is associated with reduced blood flow to several organs. Ibuprofen, another cyclo …

Background Patent ductus arteriosus (PDA) complicates the clinical course of preterm
infants and increases the risk of adverse outcomes. Indomethacin has been the standard …

Background Glioblastoma (GBM) is a highly malignant brain tumour that almost inevitably
progresses or recurs after first line standard of care. There is no consensus regarding the …