Recent advances in mass spectrometry imaging combined with artificial intelligence for spatially clarifying molecular profiles: Toward biomedical applications

H Zhang, J Zhang, C Yuan, D Zhang, D Lu… - TrAC Trends in …, 2024 - Elsevier
Mass spectrometry imaging (MSI) is an intuitive and multidimensional analysis method that
provides spatial information on molecules in tissues or cells; it is widely used in biomedical …

Advances in multimodal mass spectrometry for single‐cell analysis and imaging enhancement

SW Croslow, TJ Trinklein, JV Sweedler - FEBS letters, 2024 - Wiley Online Library
Multimodal mass spectrometry (MMS) incorporates an imaging modality with probe‐based
mass spectrometry (MS) to enable precise, targeted data acquisition and provide additional …

To image or not to image: Use of imaging mass spectrometry in biomedical lipidomics

A Maimó-Barceló, K Pérez-Romero… - Progress in lipid …, 2025 - Elsevier
Lipid imaging mass spectrometry (LIMS) allows for establishing the bidimensional
distribution of lipid species within a tissue section. One of the main advantages is the …

Promising mass spectrometry imaging: exploring microscale insights in food

X Cao, P Cong, Y Song, Y Liu, C Xue… - Critical Reviews in Food …, 2025 - Taylor & Francis
This review focused on mass spectrometry imaging (MSI), a powerful tool in food analysis,
covering its ion source schemes and procedures and their applications in food quality …

Pair-Soil-Spectra: An Approach for NIRS-Based Soil Total Nitrogen Content Detection with Feature Metrics in Cases of Small Sample Sizes

Y Wang, C Zhao, Z Xing, M Zhu, L Hao… - Analytical …, 2025 - ACS Publications
Soil total nitrogen (STN) plays an important role in plant growth, and rapid and
nondestructive detection of STN content is essential for agricultural production. Near …

Enhancing Spatial Resolution in Tandem Mass Spectrometry Ion/Ion Reaction Imaging Experiments through Image Fusion

Z Liang, Y Guo, X Diao, BM Prentice - Journal of the American …, 2024 - ACS Publications
We have recently developed a charge inversion ion/ion reaction to selectively derivatize
phosphatidylserine lipids via gas-phase Schiff base formation. This tandem mass …

Application of clustering strategy for automatic segmentation of tissue regions in mass spectrometry imaging

G Xu, S Gan, B Guo, L Yang - Rapid Communications in Mass …, 2024 - Wiley Online Library
Rationale Mass spectrometry imaging (MSI) has been widely used in biomedical research
fields. Each pixel in MSI consists of a mass spectrum that reflects the molecule feature of the …

深度学习在质谱成像数据分析中的应用研究进展

D HUANG, LIU Xinyu… - Chinese Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
质谱成像(MSI) 是一种用于表征化合物空间分布特征的方法. 随着采集方式的多样化发展和
灵敏度等的不断提高, 该方法产生的数据总量和分析复杂度呈指数增长, 给数据后处理带来了 …

Multi‐modal mass spectrometry imaging of a single tissue section

L Zhan, Y Huang, G Wang - Journal of Mass Spectrometry, 2024 - Wiley Online Library
Mass spectrometry imaging (MSI) was developed to visualize spatial chemical information
within tissues, thereby facilitating spatial multi‐omic analysis. However, due to the limited …

[HTML][HTML] SOmicsFusion: Multimodal coregistration and fusion between spatial metabolomics and biomedical imaging

A Guo, Z Chen, Y Ma, Y Lv, H Yan, F Li, Y Xing… - Artificial Intelligence …, 2024 - Elsevier
We present SOmicsFusion, a software toolbox for'fusing'spatial omics with classical
biomedical imaging modalities, capitalizing on their inherent correspondences and …