Dietary restriction impacts health and lifespan of genetically diverse mice

A Di Francesco, AG Deighan, L Litichevskiy, Z Chen… - Nature, 2024 - nature.com
Caloric restriction extends healthy lifespan in multiple species. Intermittent fasting, an
alternative form of dietary restriction, is potentially more sustainable in humans, but its …

Generalized genetic liability to substance use disorders

AP Miller, R Bogdan, A Agrawal… - The Journal of clinical …, 2024 - Am Soc Clin Investig
Lifetime and temporal co-occurrence of substance use disorders (SUDs) is common and
compared with individual SUDs is characterized by greater severity, additional psychiatric …

Mouse Genome Informatics: an integrated knowledgebase system for the laboratory mouse

RM Baldarelli, CL Smith, M Ringwald, JE Richardson… - Genetics, 2024 - academic.oup.com
Abstract Mouse Genome Informatics (MGI) is a federation of expertly curated information
resources designed to support experimental and computational investigations into genetic …

Characterization of Collaborative Cross mouse founder strain CAST/EiJ as a novel model for lethal COVID-19

CN Baker, D Duso, N Kothapalli, T Hart, S Casey… - Scientific Reports, 2024 - nature.com
Mutations in SARS-CoV-2 variants of concern (VOCs) have expanded the viral host range
beyond primates, and a few other mammals, to mice, affording the opportunity to exploit …

The 129 strain-derived passenger mutations in ACKR1-deficient mice alter the expression of PYHIN and Fc-gamma receptor genes

Z Möller-Ramon, M Aslani, N Sobczak… - Journal of leukocyte …, 2024 - academic.oup.com
Most genetically modified mice have been produced using 129 strain-derived embryonic
stem cells. Despite ample backcrosses with other strains, these may retain characteristics for …

Caractérisation génétique et fonctionnelle de la sensibilité et de la résistance innées au virus Zika chez la souris

M Bourdon - 2023 - theses.hal.science
L'infection par le virus Zika (ZIKV) chez l'Homme peut provoquer de multiples
conséquences, de l'absence de symptômes cliniques à des complications neurologiques ou …

[HTML][HTML] MVAR: A Mouse Variation Registry

B El Kassaby, F Castellanos, M Gerring… - Journal of Molecular …, 2024 - Elsevier
Abstract The Mouse Variation Registry (MVAR) resource is a scalable registry of mouse
single nucleotide variants and small indels and variant annotation. The resource accepts …

هوش مصنوعی در ژنتیک پزشکی: افزایش مشاوره ژنتیک و مراقبت از بیمار از طریق تجزیه و تحلیل داده‌های پیشرفته

صارمی, ابوطالب, عباسی, کریمی منصورآباد… - مجله تحقيقات پزشكي …, 2023‎ - saremjrm.com
Artificial Intelligence in Medical Genetics: Enhancing Genetic Counseling and Patient Care
through Advanced Data Analysis Page 1 Copyright© 2021, ASP Ins. This open-access …