Epstein-Barr virus: Biology and clinical disease

B Damania, SC Kenney, N Raab-Traub - Cell, 2022 - cell.com
Epstein-Barr virus (EBV) is a ubiquitous, oncogenic virus that is associated with a number of
different human malignancies as well as autoimmune disorders. The expression of EBV viral …

Epigenetic control of the Epstein-Barr lifecycle

R Guo, BE Gewurz - Current opinion in virology, 2022 - Elsevier
Epstein-Barr virus (EBV) infects 95% of adults worldwide, causes infectious mononucleosis,
is etiologically linked to multiple sclerosis and is associated with 200 000 cases of cancer …

[HTML][HTML] Unraveling the Aurora kinase A and Epstein-Barr nuclear antigen 1 axis in Epstein Barr virus associated gastric cancer

N Varshney, S Murmu, B Baral, D Kashyap, S Singh… - Virology, 2023 - Elsevier
Aurora kinase A (AURKA) is one of the crucial cell cycle regulators associated with gastric
cancer. Here, we explored Epstein Barr Virus-induced gastric cancer progression through …

Do Epstein–Barr virus mutations and natural genome sequence variations contribute to disease?

PJ Farrell, RE White - Biomolecules, 2021 - mdpi.com
Most of the world's population is infected by the Epstein–Barr virus (EBV), but the incidence
of the diseases associated with EBV infection differs greatly in different parts of the world …

Pseudouridylation of Epstein-Barr virus noncoding RNA EBER2 facilitates lytic replication

BA Henry, V Marchand, BT Schlegel, M Helm… - RNA, 2022 - rnajournal.cshlp.org
Epstein-Barr virus (EBV) expresses two highly abundant noncoding RNAs called EBV-
encoded RNA 1 (EBER1) and EBER2, which are preserved in all clinical isolates of EBV …

[HTML][HTML] How Epstein Barr Virus Causes Lymphomas

YF Chiu, K Ponlachantra, B Sugden - Viruses, 2024 - mdpi.com
Since Epstein–Barr Virus (EBV) was isolated 60 years ago, it has been studied clinically,
epidemiologically, immunologically, and molecularly in the ensuing years. These combined …

The central role of the ubiquitin–proteasome system in EBV-mediated oncogenesis

Y Pei, ES Robertson - Cancers, 2022 - mdpi.com
Simple Summary Epstein–Barr virus (EBV) is the first discovered human tumor virus, which
contributes to the oncogenesis of many human cancers. The ubiquitin–proteasome system …

UCHL1 promotes the proliferation of porcine granulosa cells by stabilizing CCNB1

S Shi, H Yuan, L Zhang, L Gao, L Zhao, X Zeng… - Journal of Animal …, 2024 - Springer
Background The proliferation of porcine ovarian granulosa cells (GCs) is essential to
follicular development and the ubiquitin–proteasome system is necessary for maintaining …

Pioneer factors in viral infection

E Neugebauer, AM Bastidas-Quintero… - Frontiers in …, 2023 - frontiersin.org
Pioneer factors are transcription factors sharing the fascinating ability to bind to compact
chromatin and thereby alter its transcriptional fate. Most pioneer factors are known for their …

A Polymorphism in the Epstein-Barr Virus EBER2 Noncoding RNA Drives In Vivo Expansion of Latently Infected B Cells

Y Wang, N Ungerleider, BA Hoffman, M Kara, PJ Farrell… - Mbio, 2022 - Am Soc Microbiol
The oncogenic gammaherpesviruses, including human Epstein-Barr virus (EBV), human
Kaposi's sarcoma-associated herpesvirus (KSHV), and murine gammaherpesvirus 68 …