Bacteria provide a rich source of natural products with potential therapeutic applications,
such as novel antibiotic classes or anticancer drugs. Bioactivity-guided screening of …

The biosynthesis of antibiotics and self-protection mechanisms employed by antibiotic
producers are an integral part of the growing antibiotic resistance threat. The origins of …

Microbial natural products have provided an important source of therapeutic leads and
motivated research and innovation in diverse scientific disciplines. In recent years, it has …

Bacteria of the genus Pseudomonas are ubiquitous in nature. Pseudomonads display a
fascinating metabolic diversity, which correlates with their ability to colonize an extremely …

Investigating the ecological context of microbial predator–prey interactions enables the
identification of microorganisms, which produce multiple secondary metabolites to evade …

Lipopeptides (LPs) are a prominent class of molecules among the steadily growing
spectrum of specialized metabolites retrieved from Pseudomonas, in particular soil-dwelling …

Dehydroamino acids are important structural motifs and biosynthetic intermediates for
natural products. Many bioactive natural products of nonribosomal origin contain …

The widespread emergence of antibiotic-resistant pathogens poses a severe threat to public
health. This problem becomes even worse with a coincident decline in the supply of new …

The rhizosphere is a highly competitive environment forcing bacteria to evolve strategies to
oppose their enemies. The production of toxic secondary metabolites allows bacteria to …

Microbial mixed cultures are gaining increasing attention as biotechnological production
systems, since they offer a large but untapped potential for future bioprocesses. Effects of …