[HTML][HTML] Cyanine conjugates in cancer theranostics

Y Li, Y Zhou, X Yue, Z Dai - Bioactive materials, 2021 - Elsevier
Cyanine is a meritorious fluorogenic core for the construction of fluorescent probes and its
phototherapeutic potential has been enthusiastically explored as well. Alternatively, the …

Hows and whys of tumor-seeking dyes

SM Usama, K Burgess - Accounts of chemical research, 2021 - ACS Publications
Conspectus Active targeting uses molecular fragments that bind receptors overexpressed on
cell surfaces to deliver cargoes, and this selective delivery to diseased over healthy tissue is …

Dual drugs decorated bacteria irradiate deep hypoxic tumor and arouse strong immune responses

W Chen, C He, N Qiao, Z Guo, S Hu, Y Song, H Wang… - Biomaterials, 2022 - Elsevier
Intratumoral environment as a hypoxic, non-inflamed “cold” state is difficult for many agents
to accumulate and activate the immune system. Intrinsically, facultative anaerobic …

Quicker, deeper and stronger imaging: A review of tumor-targeted, near-infrared fluorescent dyes for fluorescence guided surgery in the preclinical and clinical stages

J Jiao, J Zhang, F Yang, W Song, D Han, W Wen… - European Journal of …, 2020 - Elsevier
Cancer is a public health problem and the main cause of human mortality and morbidity
worldwide. Complete removal of tumors and metastatic lymph nodes in surgery is …

Heptamethine cyanine dye mediated drug delivery: hype or hope

PJ Choi, TIH Park, E Cooper, M Dragunow… - Bioconjugate …, 2020 - ACS Publications
This review covers the application of heptamethine cyanine dye (HMCD) mediated drug
delivery. A relatively small number of HMCDs possess tumor targeting abilities, and this has …

Site-specific albumin tagging with chloride-containing near-infrared cyanine dyes: molecular engineering, mechanism, and imaging applications

Q Su, Y Zhang, S Zhu - Chemical Communications, 2023 - pubs.rsc.org
Near-infrared dyes, particularly cyanine dyes, have shown great potential in biomedical
imaging due to their deep tissue penetration, high resolution, and minimal tissue …

Fluorescent kinase inhibitors as probes in cancer

SM Usama, B Zhao, K Burgess - Chemical Society Reviews, 2021 - pubs.rsc.org
Fluorescent dyes attached to kinase inhibitors (KIs) can be used to probe kinases in vitro, in
cells, and in vivo. Ideal characteristics of the dyes vary with their intended applications …

The use of heptamethine cyanine dyes as drug-conjugate systems in the treatment of primary and metastatic brain tumors

E Cooper, PJ Choi, WA Denny, J Jose… - Frontiers in …, 2021 - frontiersin.org
Effective cancer therapeutics for brain tumors must be able to cross the blood-brain barrier
(BBB) to reach the tumor in adequate quantities and overcome the resistance conferred by …

Involvement of the tumour necrosis factor receptor system in glioblastoma cell death induced by palbociclib-heptamethine cyanine dye conjugate

E Cooper, CRM Oyagawa, R Johnson, PJ Choi… - Cell Communication and …, 2024 - Springer
Glioblastoma is the most common and aggressive primary brain tumour in adults. The
development of anti-brain cancer agents are challenged by the blood-brain barrier and the …

Screening tumor specificity targeted by arnicolide D, the active compound of Centipeda minima and molecular mechanism underlying by integrative pharmacology

J Yao, Q Shen, M Huang, M Ding, Y Guo… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Herb-derived anti-tumor agents, such as paclitaxel and
vincristine, exert significant but varied effectivenesses towards different cancer types …