HMGB1 in health and disease

R Kang, R Chen, Q Zhang, W Hou, S Wu, L Cao… - Molecular aspects of …, 2014 - Elsevier
Complex genetic and physiological variations as well as environmental factors that drive
emergence of chromosomal instability, development of unscheduled cell death, skewed …

Molecular mechanisms of IFN-γ to up-regulate MHC class I antigen processing and presentation

F Zhou - International reviews of immunology, 2009 - Taylor & Francis
IFN-γ up-regulates MHC class I expression and antigen processing and presentation on
cells, since IFN-γ can induce multiple gene expressions that are related to MHC class I …

Fish health aspects in grouper aquaculture

R Harikrishnan, C Balasundaram, MS Heo - Aquaculture, 2011 - Elsevier
The subfamily Epinephelinae comprises groupers including 159 species under 15 genera.
Groupers enjoy a wide distribution in the Eastern Atlantic Ocean and Mediterranean Sea …

Re-Directing CD4+ T Cell Responses with the Flanking Residues of MHC Class II-Bound Peptides: The Core is Not Enough

CJ Holland, DK Cole, A Godkin - Frontiers in immunology, 2013 - frontiersin.org
Recombinant αβ T cell receptors, expressed on T cell membranes, recognize short peptides
presented at the cell surface in complex with MHC molecules. There are two main subsets of …

Disulfide reduction in the endocytic pathway: immunological functions of gamma-interferon-inducible lysosomal thiol reductase

KT Hastings, P Cresswell - Antioxidants & redox signaling, 2011 - liebertpub.com
Gamma-interferon-inducible lysosomal thiol reductase (GILT) is constitutively expressed in
most antigen presenting cells and is interferon γ inducible in other cell types via signal …

Diverse cellular and organismal functions of the lysosomal thiol reductase GILT

MP Rausch, KT Hastings - Molecular immunology, 2015 - Elsevier
Gamma-interferon-inducible lysosomal thiol reductase (GILT) is the only enzyme known to
catalyze disulfide bond reduction in the endocytic pathway. GILT facilitates the presentation …

Expanding roles for GILT in immunity

LC West, P Cresswell - Current opinion in immunology, 2013 - Elsevier
Gamma-interferon-inducible lysosomal thiol reductase (GILT), a thioredoxin-related
oxidoreductase, functions in MHC class II-restricted antigen processing and MHC class I …

Activation of ERα signaling differentially modulates IFN-γ induced HLA-class II expression in breast cancer cells

AA Mostafa, D Codner, K Hirasawa, Y Komatsu… - PLoS one, 2014 - journals.plos.org
The coordinate regulation of HLA class II (HLA-II) is controlled by the class II transactivator,
CIITA, and is crucial for the development of anti-tumor immunity. HLA-II in breast carcinoma …

Lysosomal thiol reductase negatively regulates autophagy by altering glutathione synthesis and oxidation

HS Chiang, M Maric - Free Radical Biology and Medicine, 2011 - Elsevier
Redox regulation is critical for a number of cellular functions and has been implicated in the
etiology and progression of several diseases, such as cardiovascular diseases …

Protective effects of estrogen via nanoparticle delivery to attenuate myelin loss and neuronal death after spinal cord injury

A Haque, KP Drasites, A Cox, M Capone… - Neurochemical …, 2021 - Springer
Spinal cord injury (SCI) is associated with devastating neurological deficits affecting more
than 11,000 Americans each year. Although several therapeutic agents have been …