Lines of evidence from several studies have shown that increases in life expectancy are now
accompanied by increased disability rate. The expanded lifespan of the aging population …

Adipose tissue as the largest energy reservoir and endocrine organ is essential for
maintenance of systemic glucose, lipid and energy homeostasis, but these metabolic …

Adipose tissue eosinophils (ATEs) are important in the control of obesity-associated
inflammation and metabolic disease. However, the way in which ageing impacts the …

Adipose tissue, which is the crucial energy reservoir and endocrine organ for the
maintenance of systemic glucose, lipid, and energy homeostasis, undergoes significant …

Obesity is a major risk factor for type 2 diabetes and a trigger of chronic and systemic
inflammation. Recent evidence suggests that an increased burden of senescent cells (SCs) …

The energy-burning capability of beige adipose tissue is a potential therapeutic tool for
reducing obesity and metabolic disease, but this capacity is decreased by aging. Here, we …

Age associated chronic inflammation is a major contributor to diseases with advancing age.
Adipose tissue function is at the nexus of processes contributing to age-related metabolic …

Aim Over the last decades, the shift in age distribution towards older ages and the
progressive ageing which has occurred in most populations have been paralleled by a …

Age-related impairment of neurovascular coupling (NVC;“functional hyperemia”) is a critical
factor in the development of vascular cognitive impairment (VCI). Recent geroscience …

Adipose tissue is a widely distributed organ that plays a critical role in age-related
physiological dysfunctions as an important source of chronic sterile low-grade inflammation …