Metabolic anti-cancer effects of melatonin: clinically relevant prospects
Simple Summary Metabolic reprogramming is required for both malignant transformation
and tumor development, including invasion and metastasis. Melatonin (5-methoxy-N …
and tumor development, including invasion and metastasis. Melatonin (5-methoxy-N …
Impact of FLT3-ITD allele ratio and ITD length on therapeutic outcome in cytogenetically normal AML patients without NPM1 mutation
F Chen, J Sun, C Yin, J Cheng, J Ni, L Jiang… - Bone marrow …, 2020 - nature.com
Mutations of internal tandem duplication in FMS-like tyrosine kinase 3 (FLT3-ITD) contribute
to poor prognosis in cytogenetically normal acute myeloid leukemia (CN-AML) …
to poor prognosis in cytogenetically normal acute myeloid leukemia (CN-AML) …
Poor outcome of pediatric patients with acute myeloid leukemia harboring high FLT3/ITD allelic ratios
K Qiu, X Liao, Y Liu, K Huang, Y Li, J Fang… - Nature …, 2022 - nature.com
Activating FLT3 mutations are the most common mutations in acute myeloid leukemia (AML),
but the optimal threshold of FLT3/ITD allelic ratio (AR) among pediatric AML patients …
but the optimal threshold of FLT3/ITD allelic ratio (AR) among pediatric AML patients …
[HTML][HTML] The association of FLT3-ITD gene mutation with bone marrow blast cell count, CD34, cyclin D1, Bcl-xL and hENT1 expression in acute myeloid leukemia …
Methods: We investigated FLT3-ITD mutations, bone marrow blast cell count, CD34, cyclin
D1, Bcl-xL and hENT1 expression in bone marrow aspirates from 22 de novo AML patients …
D1, Bcl-xL and hENT1 expression in bone marrow aspirates from 22 de novo AML patients …
[HTML][HTML] Distribution of chromosomal abnormalities commonly observed in adult acute myeloid leukemia in Pakistan as predictors of prognosis
Objectives The heterogenous response to treatment in acute myeloid leukemia (AML) can
be attributed largely to the difference in cytogenetic features identified in between cases …
be attributed largely to the difference in cytogenetic features identified in between cases …
FLT3-ITD allele frequency is an independent prognostic factor for poor outcome in FLT3-ITD–positive AML patients
NF Shafik, AD Darwish, RM Allam… - … Lymphoma Myeloma and …, 2021 - Elsevier
Background FMS-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) is a
molecular genetic alteration significantly affecting the clinical outcome in patients with acute …
molecular genetic alteration significantly affecting the clinical outcome in patients with acute …
FLT3-ITD Mutations in acute myeloid leukemia patients in Northeast Thailand
P Kumsaen, G Fucharoen, C Sirijerachai… - Asian Pacific Journal …, 2016 - journal.waocp.org
The FLT3-ITD mutation is one of the most frequent genetic abnormalities in acute myeloid
leukemia (AML) where it is associated with a poor prognosis. The FLT3-ITD mutation could …
leukemia (AML) where it is associated with a poor prognosis. The FLT3-ITD mutation could …
Identification of a novel mutation of the FLT3 gene located on the juxtamembrane domain from acute myeloid leukemia patients
Background FLT3 gene mutations are genetic abnormality that caused leukemogenesis.
Furthermore, presence of FLT3 mutations is associated with poor prognosis in AML. This …
Furthermore, presence of FLT3 mutations is associated with poor prognosis in AML. This …
Conformation sensitive gel electrophoresis for the detection of calreticulin mutations in BCR‐ABL1‐negative myeloproliferative neoplasms
NA Zakaria, NA Rosle, MJ Siti Asmaa… - International Journal …, 2021 - Wiley Online Library
Introduction Calreticulin (CALR) mutations in myeloproliferative neoplasms (MPN) have
been reported to be key markers in the molecular diagnosis, particularly in patients lacking …
been reported to be key markers in the molecular diagnosis, particularly in patients lacking …
Mutación FTL3-ITD y su relación con variables hematológicas y clínicas en individuos con Leucemia Mieloide Aguda
F Calderón Calle, CF Prieto Fuenmayor - 2021 - repositorio.cidecuador.org
Introducción. La Leucemia Mieloide Aguda es la neoplasia hematológica más común,
caracterizada por una proliferación incontrolada de células madre hematopoyéticas. La …
caracterizada por una proliferación incontrolada de células madre hematopoyéticas. La …