Retinal macroglial responses in health and disease

R de Hoz, B Rojas, AI Ramírez… - BioMed research …, 2016 - Wiley Online Library
Due to their permanent and close proximity to neurons, glial cells perform essential tasks for
the normal physiology of the retina. Astrocytes and Müller cells (retinal macroglia) provide …

Synapse-specific astrocyte gating of amygdala-related behavior

M Martin-Fernandez, S Jamison, LM Robin… - Nature …, 2017 - nature.com
The amygdala plays key roles in fear and anxiety. Studies of the amygdala have largely
focused on neuronal function and connectivity. Astrocytes functionally interact with neurons …

Astrocyte-neuron signaling in the mesolimbic dopamine system: the hidden stars of dopamine signaling

M Corkrum, A Araque - Neuropsychopharmacology, 2021 - nature.com
Astrocytes are fundamental components of brain information processing and possess the
ability to respond to synaptic signaling with increases in cytoplasmic calcium and modulate …

Structural and functional plasticity of astrocyte processes and dendritic spine interactions

A Perez-Alvarez, M Navarrete, A Covelo… - Journal of …, 2014 - Soc Neuroscience
Experience-dependent plasticity of synaptic transmission, which represents the cellular
basis of learning, is accompanied by morphological changes in dendritic spines. Astrocytic …

Circuit-specific signaling in astrocyte-neuron networks in basal ganglia pathways

R Martín, R Bajo-Grañeras, R Moratalla, G Perea… - Science, 2015 - science.org
Astrocytes are important regulatory elements in brain function. They respond to
neurotransmitters and release gliotransmitters that modulate synaptic transmission …

Reciprocal regulation of mitochondrial dynamics and calcium signaling in astrocyte processes

JG Jackson, MB Robinson - Journal of Neuroscience, 2015 - Soc Neuroscience
We recently showed that inhibition of neuronal activity, glutamate uptake, or reversed-
Na+/Ca2+-exchange with TTX, TFB-TBOA, or YM-244769, respectively, increases …

Insulin regulates astrocytic glucose handling through cooperation with IGF-I

AM Fernandez, E Hernandez-Garzón… - Diabetes, 2017 - Am Diabetes Assoc
Brain activity requires a flux of glucose to active regions to sustain increased metabolic
demands. Insulin, the main regulator of glucose handling in the body, has been traditionally …

The insulin‐like growth factor I receptor regulates glucose transport by astrocytes

E Hernandez‐Garzón, AM Fernandez, A Perez‐Alvarez… - Glia, 2016 - Wiley Online Library
Previous findings indicate that reducing brain insulin‐like growth factor I receptor (IGF‐IR)
activity promotes ample neuroprotection. We now examined a possible action of IGF‐IR on …

Seeing is believing – multi-scale spatio-temporal imaging towards in vivo cell biology

G Follain, L Mercier, N Osmani… - Journal of Cell …, 2017 - journals.biologists.com
Life is driven by a set of biological events that are naturally dynamic and tightly orchestrated
from the single molecule to entire organisms. Although biochemistry and molecular biology …

Miniaturized fiber-coupled confocal fluorescence microscope with an electrowetting variable focus lens using no moving parts

BN Ozbay, JT Losacco, R Cormack, R Weir, VM Bright… - Optics letters, 2015 - opg.optica.org
We report a miniature, lightweight fiber-coupled confocal fluorescence microscope that
incorporates an electrowetting variable focus lens to provide axial scanning for full three …