Biomaterials and advanced technologies for hemostatic management of bleeding

DSA Hickman, CL Pawlowski, UDS Sekhon… - Advanced …, 2018 - Wiley Online Library
Bleeding complications arising from trauma, surgery, and as congenital, disease‐
associated, or drug‐induced blood disorders can cause significant morbidities and …

Emerging materials for hemostasis

XF Li, P Lu, HR Jia, G Li, B Zhu, X Wang… - Coordination Chemistry …, 2023 - Elsevier
Severe hemorrhage has posed a serious threat to the health and even life of civilian and
military populations and brought serious economic losses. Consequently, it is imperative to …

Injectable Self‐Expanding/Self‐Propelling Hydrogel Adhesive with Procoagulant Activity and Rapid Gelation for Lethal Massive Hemorrhage Management

X Zhao, Y Huang, Z Li, J Chen, J Luo, L Bai… - Advanced …, 2024 - Wiley Online Library
Developing hydrogels that can quickly reach deep bleeding sites, adhere to wounds, and
expand to stop lethal and/or noncompressible bleeding in civil and battlefield environments …

Injectable dry cryogels with excellent blood-sucking expansion and blood clotting to cease hemorrhage for lethal deep-wounds, coagulopathy and tissue regeneration

X Zhao, Y Liang, B Guo, Z Yin, D Zhu, Y Han - Chemical Engineering …, 2021 - Elsevier
Designing expandable dry cryogels with biodegradability, rapid blood-sucking expansion
and hemostasis for lethal non-compressible hemorrhage and coagulopathy hemorrhage still …

A review on recent advances in chitosan based composite for hemostatic dressings

MA Khan, M Mujahid - International journal of biological macromolecules, 2019 - Elsevier
High mortality rate in potentially survivable casualties due to severe hemorrhage is a major
challenge in today's battlefield because technological advancements have revolutionized …

Chitosan-based hemostatic sponges as new generation hemostatic materials for uncontrolled bleeding emergency: Modification, composition, and applications

Z Liu, Y Xu, H Su, X Jing, D Wang, S Li, Y Chen… - Carbohydrate …, 2023 - Elsevier
The choice of hemostatic technique is a curial concern for surgery and as first-aid treatment
in combat. To treat uncontrolled bleeding in complex wound environments, chitosan-based …

Mussel-inspired degradable antibacterial polydopamine/silica nanoparticle for rapid hemostasis

C Liu, W Yao, M Tian, J Wei, Q Song, W Qiao - Biomaterials, 2018 - Elsevier
High-performance hemostasis becomes increasingly essential in civilian and military
trauma. However, available topical hemostats still exist various drawbacks and side-effects …

Design and development of polysaccharide hemostatic materials and their hemostatic mechanism

X Yang, W Liu, N Li, M Wang, B Liang, I Ullah… - Biomaterials …, 2017 - pubs.rsc.org
The formation of stable blood clots or hemostasis is essential to prevent major blood loss
and death from excessive bleeding. However, the body's own coagulation process is not …

Analysis of clinical trials on biomaterial and therapeutic applications of chitosan: A review

MN Kantak, SS Bharate - Carbohydrate Polymers, 2022 - Elsevier
Chitosan is a modified natural carbohydrate polymer derived from chitin that occurs in many
natural sources. It has a diverse range of applications in medical and pharmaceutical …

Chitosan‐Based Hydrogels as Antibacterial/Antioxidant/Anti‐Inflammation Multifunctional Dressings for Chronic Wound Healing

J Xu, L Chang, Y Xiong, Q Peng - Advanced Healthcare …, 2024 - Wiley Online Library
Due to repeated microbial infection, persistent inflammation, excessive oxidative stress, and
cell dysfunction, chronic wounds are difficult to heal, posing a serious threat to public health …