Abstract This International Consensus Classification and Nomenclature for the congenital
bicuspid aortic valve condition recognizes 3 types of bicuspid valves: 1. The fused type (right …

Highlights•Comprehensive aortic root anatomy is reviewed.•The interleaflet triangles
determine valvar morphology in the aortic root.•Imaging and surgical implications are …

Herein we summarize the current knowledge on the bicuspid aortic valve (BAV)-associated
aortopathy regarding clinical presentation and disease sub-classification, genetic …

Introduction While the understanding of the pathophysiology and clinical implication of
bicuspid aortic valves evolves rapidly, the natural history of unicuspid aortic valves is still …

Background Unicuspid aortic valve (UAV) is a rare disorder, often difficult to distinguish from
bicuspid aortic valve (BAV). BAV and UAV share valve pathology such as the presence of a …

Background The epithelial growth factor receptor family of tyrosine kinases modulates
embryonic formation of semilunar valves. We hypothesized that mice heterozygous for a …

The congenital bicuspid aortic valve (BAV) condition is a valvulo-aortopathy with
heterogeneous phenotypic expressions and clinical outcomes. A multitude of pre-existing …

Hypertension and congenital aortic valve malformations are frequent causes of ascending
aortic aneurysms. The molecular mechanisms of aneurysm formation under these …

Unicuspid aortic valve (UAV) is a rare malformation that is often difficult to distinguish from a
bicuspid aortic valve (BAV) with commissural fusion by echocardiography or intraoperative …

Unicuspid aortic valve (UAV) is a rare congenital malformation that affects 5% of patients
undergoing aortic stenosis surgery. It has two subtypes, acommissural and unicommissural …