RNA‐Selective Small‐Molecule Ligands: Recent Advances in Live‐Cell Imaging and Drug Discovery
KH Chan, Y Wang, BX Zheng, W Long, X Feng… - …, 2023 - Wiley Online Library
RNA structures, including those formed from coding and noncoding RNAs, alternative to
protein‐based drug targets, could be a promising target of small molecules for drug …
protein‐based drug targets, could be a promising target of small molecules for drug …
Translating G-quadruplex ligands from bench to bedside: a Stephen Neidle's legacy
D Monchaud - Medicinal Chemistry Research, 2024 - Springer
Abstract DNA and RNA G-quadruplexes (G4s) are alternative nucleic acid structures that
can fold from thousands of guanine (G)-rich sequences in the genome and transcriptome of …
can fold from thousands of guanine (G)-rich sequences in the genome and transcriptome of …
Identification and detection of conserved G-quadruplex in monkeypox virus using conformation specific fluorogenic probe
S Pratihar, R Venkatesh, MN Mattath… - Chemical …, 2024 - pubs.rsc.org
Identifying distinct noncanonical structures in pathogenic genomes is crucial for developing
new diagnostic tools. This study uncovers stable G-quadruplex (GQ) structures in conserved …
new diagnostic tools. This study uncovers stable G-quadruplex (GQ) structures in conserved …
Tuning the push-pull dyes: Construction of polarity insensitive probes for G4 DNA
HW Chen, JZ Li, LY Li, ZK Li, XF Yu, HJ Wang… - Dyes and …, 2024 - Elsevier
We report here the design and synthesis of two new polarity-insensitive push-pull dyes TCP-
SO 3 and TCP-COOH and developed as fluorescent probes for G-quadruplex (G4) DNAs …
SO 3 and TCP-COOH and developed as fluorescent probes for G-quadruplex (G4) DNAs …
D-π-A type fluorescent dyes: Effect of π-bridge units on optical and G4 DNA binding properties
HW Chen, HW Cao, JZ Li, YS Chen, LY Li, ZK Li… - … Acta Part A: Molecular …, 2024 - Elsevier
Fluorescent solvatochromic dyes that are sensitive to the nature of local microenvironmental,
have been explored as probes in applications ranging from the imaging biomolecules to …
have been explored as probes in applications ranging from the imaging biomolecules to …