IBD is a chronic inflammatory condition of the gastrointestinal tract encompassing two main
clinical entities: Crohn's disease and ulcerative colitis. Although Crohn's disease and …

Leukocyte trafficking to the small and large intestines is tightly controlled to maintain
intestinal immune homeostasis, mediate immune responses, and regulate inflammation. A …

Abstract Forkhead box P3 (FOXP3)+ regulatory T (TReg) cells prevent autoimmune disease,
maintain immune homeostasis and modulate immune responses during infection. To …

Tregs not only keep immune responses to autoantigens in check, but also restrain those
directed toward pathogens and the commensal microbiota. Control of peripheral immune …

В монографии приведены сведения по роли цитокинов в регуляции физиологических
процессов, защитных реакций организма и в патогенезе иммунопатологических …

Foxp3+ regulatory T cells (Tregs) are essential for preventing autoimmunity and
uncontrolled inflammation, and they modulate immune responses during infection and the …

Regulatory T (T reg) cells play key roles in various immune responses. For example, T reg
cells contribute to the complex pathogenesis of inflammatory bowel disease (IBD), which …

Myocardial infarction triggers an inflammatory reaction that is involved in cardiac
remodeling. Cardiac repair is dependent on regulatory mechanisms that suppress …

Migration and trafficking receptors of Th17 cells to mucosal tissues have been unclear. We
report that Th17 cells preferentially migrate to the intestine and associated lymphoid tissues …

The SAMP1/YitFc mouse strain represents a model of Crohn's disease (CD)-like ileitis that is
ideal for investigating the pathogenesis of chronic intestinal inflammation. Different from the …