In some patients with major depressive disorder (MDD), individual illness characteristics
appear consistent with those of a neuroprogressive illness. Features of neuroprogression …

Lithium has been used for over half a century for the treatment of bipolar disorder as the
archetypal mood stabilizer, and has a wealth of empirical evidence supporting its efficacy in …

Context Although differences in clinical characteristics exist between major depressive
disorder (MDD) and bipolar disorder (BD), consistent structural brain abnormalities that …

The ability to regulate emotions is an important part of adaptive functioning in society.
Advances in cognitive and affective neuroscience and biological psychiatry have facilitated …

Objective. So far, there have been no attempts to integrate the growing number of all brain
volumetric magnetic resonance imaging studies in depression. In this comprehensive meta …

The anterior cingulate cortex (ACC) ventral to the genu of the corpus callosum has been
implicated in the modulation of emotional behavior on the basis of neuroimaging studies in …

Previous meta-analyses of structural MRI studies have shown diffuse cortical and sub-
cortical abnormalities in unipolar depression. However, the presence of duplicate …

The subcallosal cingulate gyrus (SCG), including Brodmann area 25 and parts of 24 and 32,
is the portion of the cingulum that lies ventral to the corpus callosum. It constitutes an …

BACKGROUND: A number of studies have reported evidence of cognitive deficits in
euthymic bipolar patients. Qualitative reviews of the literature have indicated impairments in …

BACKGROUND: While there is evidence to suggest that major depressive disorder (MDD) is
associated with structural brain abnormalities, the precise nature of these abnormalities …