Systematic review and analysis of human proteomics aging studies unveils a novel proteomic aging clock and identifies key processes that change with age

AA Johnson, MN Shokhirev, T Wyss-Coray… - Ageing research …, 2020 - Elsevier
The development of clinical interventions that significantly improve human healthspan
requires robust markers of biological age as well as thoughtful therapeutic targets. To …

Zebrafish as the toxicant screening model: Transgenic and omics approaches

KP Lai, Z Gong, WKF Tse - Aquatic Toxicology, 2021 - Elsevier
The production of large amounts of synthetic industrial and biomedical compounds, together
with environmental pollutants, poses a risk to our ecosystem and induces negative effects on …

Endocrine disruption by azole fungicides in fish: A review of the evidence

T Huang, Y Zhao, J He, H Cheng… - Science of The Total …, 2022 - Elsevier
Azole fungicides are widely used chemicals in agriculture and medicine. Their antifungal
activity involves inhibition of steroid biosynthesis via inhibition of several cytochrome p 450 …

[HTML][HTML] Endocrine disruptors in teleosts: Evaluating environmental risks and biomarkers

S Kar, P Sangem, N Anusha… - Aquaculture and Fisheries, 2021 - Elsevier
Endocrine disruptors (EDs) are synthetic or natural chemical molecules occurring in
environment that have the potential to impart adverse effects on homeostasis of endocrine …

Short-Term Test for Toxicogenomic Analysis of Ecotoxic Modes of Action in Lemna minor

A Loll, H Reinwald, SU Ayobahan… - Environmental …, 2022 - ACS Publications
In the environmental risk assessment of substances, toxicity to aquatic plants is evaluated
using, among other methods, the 7 day Lemna sp. growth inhibition test following the OECD …

[HTML][HTML] Toxicogenomic fin (ger) prints for thyroid disruption AOP refinement and biomarker identification in zebrafish embryos

H Reinwald, A König, SU Ayobahan, J Alvincz… - Science of the Total …, 2021 - Elsevier
Endocrine disruption (ED) can trigger far-reaching effects on environmental populations,
justifying a refusal of market approval for chemicals with ED properties. For the hazard …

Exposure to acetaminophen impairs gametogenesis and fertility in zebrafish (Danio rerio)

DP Moreira, YM Ribeiro, CS Ferreira… - Archives of …, 2023 - Springer
Acetaminophen (ACE; paracetamol) is one of the most widely used nonsteroidal anti-
inflammatory drugs worldwide and is often found in aquatic systems, where it can act on …

[HTML][HTML] Comparison of sample preparation methods for shotgun proteomic studies in aquaculture species

MJ Araújo, ML Sousa, AB Felpeto, MV Turkina… - Proteomes, 2021 - mdpi.com
Proteomics has been recently introduced in aquaculture research, and more methodological
studies are needed to improve the quality of proteomics studies. Therefore, this work aims to …

Zebrafish as a translational model: an experimental alternative to study the mechanisms involved in anosmia and possible neurodegenerative aspects of COVID-19?

KCM Costa, TAV Brigante, GG Fernandes… - eneuro, 2021 - eneuro.org
The Coronavirus disease-2019 (COVID-19) presents a variability of clinical symptoms,
ranging from asymptomatic to severe respiratory and systemic conditions. In a cohort of …

Refinement of an OECD test guideline for evaluating the effects of endocrine disrupting chemicals on aromatase gene expression and reproduction using novel …

J De Oliveira, E Chadili, B Piccini, C Turies… - Aquatic Toxicology, 2020 - Elsevier
Transgenic fish are powerful models that can provide mechanistic information regarding the
endocrine activity of test chemicals. In this study, our objective was to use a newly …